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Gene Expression Data
Assay Details
Assay
Reference: J:326811 Rodriguez KF, et al., Somatic cell fate maintenance in mouse fetal testes via autocrine/paracrine action of AMH and activin B. Nat Commun. 2022 Jul 15;13(1):4130
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328376
Gene symbol: Dmrt1
Gene name: doublesex and mab-3 related transcription factor 1
Antibody: anti-DMRT1
Results
Specimen 1F: postnatal month 5 (more )
Note: Control XY. Triple labeled: blue - Dmrt1; green - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present 1F
Specimen 1H: postnatal month 5; Amhtm1Bhr/Amhtm1Bhr, Inhbbtm1Jae/Inhbbtm1Jae (more )
Note: dKO XY. Triple labeled: blue - Dmrt1; green - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Level Pattern Image Note
TS28: gonad Present Regionally restricted 1H Expression in ovotestis which contained seminiferous tubules in center and ovarian structures in poles.
Specimen 2J: embryonic day 15.5 (more )
Note: Control XY. Triple labeled: green - Dmrt1; blue - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present Regionally restricted 2J Expression in cells outlining characteristic cord structures.
Specimen 2K: embryonic day 15.5; Amhtm1Bhr/Amhtm1Bhr, Inhbbtm1Jae/Inhbbtm1Jae (more )
Note: dKO XY. Triple labeled: green - Dmrt1; blue - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Cell Type Level Pattern Image Note
TS23: gonad Present Regionally restricted 2K Characteristic cord structures mostly disintegrated in poles of gonad.
TS23: Sertoli cell Sertoli cell Present 2K
Specimen 2L: embryonic day 15.5 (more )
Note: Control XX. Triple labeled: green - Dmrt1; blue - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Level Pattern Image Note
TS23: ovary Absent 2L
Specimen 2M: embryonic day 15.5 (more )
Note: Control XY. Triple labeled: green - Dmrt1; blue - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 2M Expression in cells outlining characteristic cord structures.
Specimen 2N: embryonic day 15.5; Amhtm1Bhr/Amhtm1Bhr, Inhbbtm1Jae/Inhbbtm1Jae (more )
Note: dKO XY. Triple labeled: green - Dmrt1; blue - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Level Pattern Image Note
TS23: gonad Present Regionally restricted 2N Characteristic chord structures mostly disintegrated in poles of gonad.
Specimen 2O: embryonic day 15.5 (more )
Note: Control XX. Triple labeled: green - Dmrt1; blue - Gcna (assay MGI:7328377); pink - Foxl2 (assay MGI:7328378).
Structure Level Pattern Image Note
TS23: ovary Absent 2O
Specimen S2C: embryonic day 15.5 (more )
Note: Control XY. Double labeled: green - Dmrt1; blue - Foxl2 (assay MGI:7328378).
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present S2C
Specimen S2D: embryonic day 15.5; Amhtm1Bhr/Amhtm1Bhr, Inhbbtm1Jae/Inhbbtm1Jae (more )
Note: dKO XY. Double labeled: green - Dmrt1; blue - Foxl2 (assay MGI:7328378).
Structure Cell Type Level Pattern Image Note
TS23: gonad Present S2D
TS23: Sertoli cell Sertoli cell Present S2D
Specimen S2E: embryonic day 15.5 (more )
Note: Control XX. Double labeled: green - Dmrt1; blue - Foxl2 (assay MGI:7328378).
Structure Level Pattern Image Note
TS23: ovary Absent S2E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory