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Gene Expression Data
Assay Details
Assay
Reference: J:311932 White AK, et al., Trp53 ablation fails to prevent microcephaly in mouse pallium with impaired minor intron splicing. Development. 2021 Oct 15;148(20):dev199591
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7327196
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen 6A' Control: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11+ (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS20: pallium Absent 6A' Control
Specimen 6A' Rnu11 cKO: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS20: pallium Present Single cells 6A' Rnu11 cKO
Specimen 6A' dKO: embryonic day 12.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS20: pallium Absent 6A' dKO
Specimen 6A'' Control: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11+ (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS21: pallium Absent 6A'' Control
Specimen 6A'' Rnu11 cKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS21: pallium Present Single cells 6A'' Rnu11 cKO
Specimen 6A'' dKO: embryonic day 13.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS21: pallium Absent 6A'' dKO
Specimen 6A''' Control: embryonic day 14.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11+ (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS22: pallium Absent 6A''' Control
Specimen 6A''' Rnu11 cKO: embryonic day 14.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS22: pallium Present 6A''' Rnu11 cKO
Specimen 6A''' dKO: embryonic day 14.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS22: pallium Present Single cells 6A''' dKO
Specimen S6A Control: embryonic day 15.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11+ (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS23: pallium Absent S6A Control
Specimen S6A Rnu11 cKO: embryonic day 15.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS23: pallium Present Single cells S6A Rnu11 cKO
Specimen S6A dKO: embryonic day 15.5; Emx1tm1(cre)Krj/Emx1+, Rnu11tm1.1Rank/Rnu11tm1.1Rank, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant. Triple labeled: magenta - Casp3; green - H2ax (assay MGI:7327192); TUNEL (yellow).
Structure Level Pattern Image Note
TS23: pallium Present Single cells S6A dKO
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory