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Gene Expression Data
Assay Details
Assay
Reference: J:319482 Li J, et al., Limb development genes underlie variation in human fingerprint patterns. Cell. 2022 Jan 6;185(1):95-112.e18
Assay type: RNA in situ
MGI Accession ID: MGI:7312011
Gene symbol: Mecom
Gene name: MDS1 and EVI1 complex locus
Probe: Mm-Mecom (432231)
Probe preparation: Antisense labelled with fluorescein RNA
Visualized with: Fluorescein
Results
Specimen 3E E11.5: embryonic day 11.5 (more )
Note: Double labeled: green - Mecom; magenta - Prrx1 (assay MGI:7312019).
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present 3E E11.5
Specimen 3E E13.5: embryonic day 13.5 (more )
Note: Double labeled: green - Mecom; magenta - Prrx1 (assay MGI:7312019).
Structure Level Pattern Image Note
TS21: forelimb digit mesenchyme Present 3E E13.5 Co-expressed with Prrx1.
TS21: limb cartilage condensation Present 3E E13.5
Specimen 3E E15.5: embryonic day 15.5 (more )
Note: Double labeled: green - Mecom; magenta - Prrx1 (assay MGI:7312019).
Structure Level Pattern Image Note
TS23: forelimb digit mesenchyme Present 3E E15.5 Co-expressed with Prrx1.
TS23: limb cartilage condensation Absent 3E E15.5
Specimen 3E E17.5: embryonic day 17.5 (more )
Note: Double labeled: green - Mecom; magenta - Prrx1 (assay MGI:7312019).
Structure Level Pattern Image Note
TS25: forelimb digit mesenchyme Present 3E E17.5 Reduced expression. Co-expressed with Prrx1.
TS25: limb cartilage condensation Absent 3E E17.5
Specimen S3E: embryonic day 13.5 (more )
Note: Triple labeled: green - Mecom; magenta - Prrx1 (assay MGI:7312019); Cyan - Krt14 (assay MGI:7312045).
Structure Level Pattern Image Note
TS21: digit mesenchyme Present S3E left , S3E upper right , S3E lower right Co-expressed with Prrx1.
TS21: limb cartilage condensation Present S3E left , S3E lower right , S3E upper right
TS21: digit epithelium Absent S3E upper right , S3E left , S3E lower right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory