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Gene Expression Data
Assay Details
Assay
Reference: J:88590 Clamp MF, et al., Developmental analyses of 5A11/Basigin, 5A11/Basigin-2 and their putative binding partner MCT1 in the mouse eye. Exp Eye Res. 2004 Apr;78(4):777-89
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7310269
Gene symbol: Slc16a1
Gene name: solute carrier family 16 (monocarboxylic acid transporters), member 1
Antibody: anti-MCT1
Detection system: Secondary antibody coupled to Cy5
Results
Specimen 1A: embryonic day 12.0 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS20: neural retina Strong 1A
TS20: pigmented retinal epithelium Strong 1A
TS20: eye anterior segment Strong Regionally restricted 1A Expression is in the pre-ciliary and pre-iris anterior margin of the retina.
TS20: cornea epithelium Present 1A
TS20: lens vesicle epithelium Present 1A
TS20: lens vesicle Present Regionally restricted 1A Expression is in the anterior portion.

Specimen 1B: embryonic day 15.0 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS23: neural retina Strong 1B
TS23: retina Strong Regionally restricted 1B Expression is strongest at the anterior margin of the retina.

Specimen 2A: embryonic day 18.0 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS26: retina Very strong Regionally restricted 2A Expression was most intense on the tissue continuous with the anterior tip of the neural retina bordering the ciliary-pigmented epithelium. Expression was weak in the invagination.
TS26: pigmented retinal epithelium Present 2A Expression is at the apical membrane,

Specimen 2B: postnatal day 1 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS27: ciliary body Very strong Regionally restricted 2B Expression is on the non-pigmented epithelial cells on the surface of the developing ciliary process.
TS27: pigmented retinal epithelium Present Regionally restricted 2B Expression is at the basal surface of pigmented epithelium.

Specimen 2C: postnatal day 7 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS28: retina epithelium Strong Regionally restricted 2C Expression is in the non-pigmented epithelium.
TS28: ciliary body Present Regionally restricted 2C Expression is at the apposed basal surface of the folded pigmented epithelium of the two ciliary processes.

Specimen 2D: postnatal day 14 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS28: retina epithelium Strong Regionally restricted 2D Expression is in the non-pigmented epithelium. Expression is absent from the basal side of the retinal pigmented epithelium and begins to be evident on the basal side of the ciliary pigmented epithelium.
TS28: ciliary body Strong 2D
TS28: pigmented retinal epithelium Strong Regionally restricted 2D Expression is apical.

Specimen 3A: postnatal day 1 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS27: retina ganglion cell layer Strong 3A
TS27: pigmented retinal epithelium Present Regionally restricted 3A Expression is apical.
TS27: neural retina Weak Regionally restricted 3A Expression is in undifferentiated neuroblastic tissue.

Specimen 3C: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: pigmented retinal epithelium Present Regionally restricted 3C Expression is apical.

Specimen 4A: postnatal day 7 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Cell Type Level Pattern Image Note
TS28: pigmented retinal epithelium Very strong Regionally restricted 4A Expression is apical.
TS28: retina outer nuclear layer Strong 4A
TS28: retina inner nuclear layer Mueller cell Present Non-Uniform 4A Expression is stronger in the anterior half. Expression is in Mueller cells near the optic nerve and decreases and becomes absent in undifferentiated cells anteriorly.
TS28: retina ganglion cell layer Present 4A

Specimen 4B: postnatal day 7 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Cell Type Level Pattern Image Note
TS28: pigmented retinal epithelium Very strong Regionally restricted 4B Expression is apical.
TS28: retina ganglion cell layer Present 4B
TS28: retina outer nuclear layer Present 4B
TS28: retina inner nuclear layer Mueller cell Present Non-Uniform 4B Expression is stronger in the anterior portion .Expression is in Mueller cells near the optic nerve and decreases and becomes absent in undifferentiated cells anteriorly.

Specimen 4C: postnatal day 9 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Cell Type Level Pattern Image Note
TS28: retina ganglion cell layer Strong 4C
TS28: retina nerve fiber layer Strong 4C
TS28: retina inner nuclear layer Mueller cell Strong Non-Uniform 4C Expression is stronger in the anterior half of the inner nuclear layer.
TS28: retina outer plexiform layer Present 4C

Specimen 4D: postnatal day 9 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Cell Type Level Pattern Image Note
TS28: retina ganglion cell layer Strong 4D
TS28: retina nerve fiber layer Strong 4D
TS28: photoreceptor layer inner segment Present 4D
TS28: photoreceptor layer outer segment Present 4D
TS28: retina inner nuclear layer Mueller cell Present 4D Expression is stronger in the anterior half of the inner nuclear layer.

Specimen 5A: postnatal day 14 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS28: photoreceptor layer outer segment Very strong 5A
TS28: retina ganglion cell layer Strong 5A
TS28: retina inner nuclear layer Strong Non-Uniform 5A Expression is stronger in the anterior half.
TS28: retina inner plexiform layer Present Regionally restricted 5A Expression is in three prominent bands.
TS28: pigmented retinal epithelium Present Regionally restricted 5A Expression is apical.
TS28: photoreceptor layer inner segment Moderate 5A

Specimen 5B: postnatal day 21 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS28: photoreceptor layer outer segment Very strong 5B Expression is in microvilli that interdigitate into the outer segment from the retinal pigmented epithelium.
TS28: photoreceptor layer inner segment Present 5B

Specimen 6B: postnatal day 21 (more )
Note: Double labeled: blue - Slc16a1; green - Bsg (assay MGI:7294542).
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 6C , 6B Expression is apical. Anterior to the ora serrata expression is at the basal surface of the ciliary pigmented epithelium.
TS28: photoreceptor layer inner segment Present 6B , 6C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory