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Gene Expression Data
Assay Details
Assay
Reference: J:317003 Fregeac J, et al., Loss of the neurodevelopmental disease-associated gene miR-146a impairs neural progenitor differentiation and causes learning and memory deficits. Mol Autism. 2020 Mar 30;11(1):22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7293273
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6 (#PRB-278P; #30130, #901301)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1a +/+: embryonic day 14.5 (more )
Note: Double labeled: red - Pax6; green - Eomes (assay MGI:7293274).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex radial glial cell Present Regionally restricted 1a Pax6 +/+ , 1a Merge +/+ Expression is in apical radial glial cells.
Specimen 1a -/-: embryonic day 14.5; Mir146tm1.1Bal/Mir146tm1.1Bal (more )
Note: Double labeled: red - Pax6; green - Eomes (assay MGI:7293274).
Structure Cell Type Level Pattern Image Note
TS22: cerebral cortex radial glial cell Present 1a Pax6 -/- , 1a Merge -/- There is a decrease in the number of positive cells compared to control littermates.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/09/2025
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