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Gene Expression Data
Assay Details
Assay
Reference: J:323825 Giffen KP, et al., Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction. Sci Adv. 2022 Apr 8;8(14):eabk0942
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7284092
Gene symbol: Slc7a14
Gene name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
Antibody: anti-Slc7a14 (HPA045929)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1B P3 left: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear outer hair cell Present 1B P3 left
Specimen 1B P3 right: postnatal day 3 (more )
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear outer hair cell Present 1B P3 right
Specimen 1B P7: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear outer hair cell Present 1B P7
Specimen 1B P20 left: postnatal day 20 (more )
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Present 1B P20 left
Specimen 1B P20 right: postnatal day 20 (more )
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Present 1B P20 right
Specimen 1C P4: postnatal day 4 (more )
Note: Double labeled: red - Slc7a14; white - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear outer hair cell Present 1C P4
Specimen 1C P12: postnatal day 12 (more )
Note: Double labeled: red - Slc7a14; white - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Present 1C P12
Specimen 1C P21: postnatal day 21 (more )
Note: Double labeled: red - Slc7a14; white - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Present 1C P21
Specimen 1C P30: postnatal day 30 (more )
Note: Double labeled: red - Slc7a14; white - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Strong 1C P30
Specimen 1C P60: postnatal day 60 (more )
Note: Double labeled: red - Slc7a14; white - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti cochlear inner hair cell Strong 1C P60
Specimen 2E: postnatal day 60 (more )
Note: Double labeled: magenta - Slc7a14; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 2E
Specimen S1A Base: postnatal day 30 (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Strong S1A Base Expression in inner hair cells extends from the base of the cochlea to the apex.
Specimen S1A Apex: postnatal day 30 (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Strong S1A Apex Expression in inner hair cells extends from the base of the cochlea to the apex.
Specimen S1C P3: postnatal day 3 (more )
Note: Double labeled: magenta - Slc7a14; green - Nefm (assay MGI:7284157).
Structure Cell Type Level Pattern Image Note
TS27: cochlear ganglion spiral ganglion neuron Absent S1C P3
Specimen S1C P14: postnatal day 14 (more )
Note: Double labeled: magenta - Slc7a14; green - Nefm (assay MGI:7284157).
Structure Cell Type Level Pattern Image Note
TS28: cochlear ganglion spiral ganglion neuron Absent S1C P14
Specimen S1C P30: postnatal day 30 (more )
Note: Double labeled: magenta - Slc7a14; green - Nefm (assay MGI:7284157).
Structure Cell Type Level Pattern Image Note
TS28: cochlear ganglion spiral ganglion neuron Absent S1C P30
Specimen S1D: postnatal day 30 (more )
Structure Cell Type Level Pattern Image Note
TS28: photoreceptor layer Present S1D
TS28: retina ganglion cell layer retinal ganglion cell Present S1D
Specimen S1E: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: hippocampus Present S1E
Specimen S1F: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present S1F
Specimen S3C: postnatal (more )
Note: Double labeled: red - Slc7a14; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S3C
Specimen S3D: postnatal; Slc7a14em1Jqu/Slc7a14em1Jqu (more )
Note: Double labeled: red - Slc7a14; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Absent S3D
Specimen S3H: postnatal (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present S3H
Specimen S3I: postnatal; Slc7a14em1Jin/Slc7a14em1Jin (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Weak S3I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory