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Gene Expression Data
Assay Details
Assay
Reference: J:323825 Giffen KP, et al., Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction. Sci Adv. 2022 Apr 8;8(14):eabk0942
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7284089
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1A P0: postnatal day 0 (more )
Note: Double labeled: white - Myo7a; red - Slc7a14 (assay MGI:7284090).
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti auditory hair cell Present 1A P0
Specimen 1A P12: postnatal day 12 (more )
Note: Double labeled: white - Myo7a; red - Slc7a14 (assay MGI:7284090).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti auditory hair cell Present 1A P12
Specimen 1A P21: postnatal day 21 (more )
Note: Double labeled: white - Myo7a; red - Slc7a14 (assay MGI:7284090).
Structure Cell Type Level Pattern Image Note
TS28: organ of Corti auditory hair cell Present 1A P21
Specimen 4J 2-month wild type: postnatal month 2 (more )
Note: Low apical turn region.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4J 2-month wild type
Specimen 4J 2-month knock-in: postnatal month 2; Slc7a14em1Jin/Slc7a14em1Jin (more )
Note: Low apical turn region.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4J 2-month knock-in
Specimen 4J 3-month wild type: postnatal month 3 (more )
Note: Low apical turn region.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4J 3-month wild type
Specimen 4J 3-month knock-in: postnatal month 3; Slc7a14em1Jin/Slc7a14em1Jin (more )
Note: Low apical turn region.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4J 3-month knock-in
Specimen 4K 2-month wild type: postnatal month 3 (more )
Note: Double labeled: magenta - Myo7a; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4K 2-month wild type
Specimen 4K 2-month knock-in: postnatal month 2; Slc7a14em1Jin/Slc7a14em1Jin (more )
Note: Double labeled: magenta - Myo7a; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4K 2-month knock-in
Specimen 4K 3-month wild type: postnatal month 3 (more )
Note: Double labeled: magenta - Myo7a; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4K 3-month wild type
Specimen 4K 3-month knock-in: postnatal month 3; Slc7a14em1Jin/Slc7a14em1Jin (more )
Note: Double labeled: magenta - Myo7a; green - F-actin.
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 4K 3-month knock-in
Specimen S2A: embryonic day 18.5 (more )
Note: Double labeled: green - Myo7a; red - Slc7a14 (assay MGI:7284090).
Structure Level Pattern Image Note
TS26: inner ear vestibular component Ambiguous S2A
Specimen S2B: postnatal day 7 (more )
Note: Double labeled: green - Myo7a; red - Slc7a14 (assay MGI:7284090).`
Structure Level Pattern Image Note
TS28: inner ear vestibular component Ambiguous S2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory