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Gene Expression Data
Assay Details
Assay
Reference: J:278471 Nakanishi H, et al., Tmc2 expression partially restores auditory function in a mouse model of DFNB7/B11 deafness caused by loss of Tmc1 function. Sci Rep. 2018 Aug 14;8(1):12125
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7266315
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 7B Tmc1 delta/delta Apical: postnatal day 16; Tmc1tm1.1Ajg/Tmc1tm1.1Ajg (more )
Note: Double labeled: red - Myo7a; green - prestin (Slc26a5 assay MGI:7266314).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 7B Tmc1 delta/delta Apical
TS28: cochlea cochlear outer hair cell Present 7B Tmc1 delta/delta Apical
Specimen 7B Tmc1 delta/delta Middle: postnatal day 16; Tmc1tm1.1Ajg/Tmc1tm1.1Ajg (more )
Note: Double labeled: red - Myo7a; green - prestin (Slc26a5 assay MGI:7266314).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 7B Tmc1 delta/delta Middle
TS28: cochlea cochlear outer hair cell Present 7B Tmc1 delta/delta Middle
Specimen 7B Tmc1 delta/delta Basal: postnatal day 16; Tmc1tm1.1Ajg/Tmc1tm1.1Ajg (more )
Note: Double labeled: red - Myo7a; green - prestin (Slc26a5 assay MGI:7266314).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 7B Tmc1 delta/delta Basal
TS28: cochlea cochlear outer hair cell Present 7B Tmc1 delta/delta Basal
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory