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Gene Expression Data
Assay Details
Assay
Reference: J:316552 Radojevic V, et al., Expression and localization of somatostatin receptor types 3, 4 and 5 in the wild-type, SSTR1 and SSTR1/SSTR2 knockout mouse cochlea. Cell Tissue Res. 2014 Dec;358(3):717-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7264354
Gene symbol: Sstr3
Gene name: somatostatin receptor 3
Antibody: anti-SSTR3
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1b: embryonic day 14.0 (more )
Note: Double labeled: red - Sstr3; green - Hes6 (assay MGI:7264353).
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present Regionally restricted 1b Expression in thickened epithelial cells located in Kolliker's organ in cochlear duct.
Specimen 1c: embryonic day 17.0 (more )
Note: Double labeled: red - Sstr3; green - Hes6 (assay MGI:7264353).
Structure Cell Type Level Pattern Image Note
TS25: cochlear duct epithelium Ambiguous 1c Authors do not describe expression pattern.
TS25: cochlea auditory hair cell Absent 1c No expression in hair cells.
Specimen 3a: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cochlear ganglion Present 3a
TS28: organ of Corti Present 3a
Specimen 3b: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Strong Regionally restricted 3b Prominent expression in apical part of inner hair cells and outer hair cells
TS28: cochlea cochlear outer hair cell Strong Regionally restricted 3b Prominent expression in apical part of inner hair cells and outer hair cells
TS28: organ of Corti pillar cell Strong 3b
TS28: cochlear ganglion Strong Regionally restricted 3b Expression in spiral ganglion cell bodies.
Specimen 5a: postnatal adult (more )
Note: Double labeled: red - Sstr3; green - Myo7a (assay MGI:7264358).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 5a
TS28: cochlea cochlear outer hair cell Present 5a
TS28: cochlea supporting cell of cochlea Present 5a
Specimen 5b: postnatal adult; Sstr1tm1Dric/Sstr1tm1Dric (more )
Note: Double labeled: red - Sstr3; green - Myo7a (assay MGI:7264358).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 5b No difference between wild type and Sstr1 knockout mice.
TS28: cochlea cochlear outer hair cell Present 5b No difference between wild type and Sstr1 knockout mice.
TS28: cochlea supporting cell of cochlea Present 5b No difference between wild type and Sstr1 knockout mice.
Specimen 5c: postnatal adult; Sstr1tm1Dric/Sstr1tm1Dric, Sstr2tm1Rgs/Sstr2tm1Rgs (more )
Note: Double labeled: red - Sstr3; green - Myo7a (assay MGI:7264358).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Weak 5c Expression restricted to inner hair cells and outer hair cells. Expression reduced compared to wild type.
TS28: cochlea cochlear outer hair cell Weak 5c Expression restricted to inner hair cells and outer hair cells. Expression reduced compared to wild type.
TS28: organ of Corti Deiter's cell Absent 5c
TS28: organ of Corti pillar cell Absent 5c
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/07/2025
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