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Gene Expression Data
Assay Details
Assay
Reference: J:311536 Kim BJ, et al., RERE deficiency causes retinal and optic nerve atrophy through degeneration of retinal cells. Dev Dyn. 2021 Oct;250(10):1398-1409
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7262890
Gene symbol: Pou4f2
Gene name: POU domain, class 4, transcription factor 2
Antibody: Anti-Brn-3b/BRN3B/POU4F2 (D-8) sc-514474
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Alexa Fluor 488
Results
Specimen 1F: embryonic day 17.5 (more )
Note: Double labeled: green - Pou4f2; red - Rere (assay MGI:7262882).
Structure Cell Type Level Pattern Image Note
TS25: retina layer retinal ganglion cell Present Regionally restricted 1F , 1G Expression was detected in the retinal ganglion cell layer. A subset of Pou4f2-positive cells were also Rere-positive.
Specimen 2B Rere+/+: embryonic day 17.5 (more )
Note: Double labeled: green - Pou4f2; red - Rere (assay MGI:7262882).
Structure Level Pattern Image Note
TS25: retina layer Present 2B Brn3b +/+ , 2B Rere/Brn3b +/+
Specimen 2B Rereom/eyes3: embryonic day 17.5; Rereeyes3/Rereom (more )
Note: Double labeled: green - Pou4f2; red - Rere (assay MGI:7262882).
Structure Level Pattern Image Note
TS25: retina layer Present 2B Rere/Brn3b om/eyes3 , 2B Brn3b om/eyes3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory