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Gene Expression Data
Assay Details
Assay
Reference: J:317089 Du J, et al., FHL2 mediates tooth development and human dental pulp cell differentiation into odontoblasts, partially by interacting with Runx2. J Mol Histol. 2016 Apr;47(2):195-202
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258372
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Antibody: anti-Runx2
Results
Specimen 1C: embryonic day 13.5 (more )
Note: Bud stage of tooth development. Double labeled: green - Runx2; red - Fhl2 (assay MGI:7258371).
Structure Level Pattern Image Note
TS21: enamel organ Present 1C , 1F , 1E
TS21: molar mesenchyme Present Regionally restricted 1C , 1E , 1F Expression is in the mesenchyme underlying the enamel organ and is localized in the nuclei.
Specimen 2C: embryonic day 14.5 (more )
Note: Cap stage of tooth development. Double labeled: green - Runx2; red - Fhl2 (assay MGI:7258371).
Structure Level Pattern Image Note
TS22: dental sac Present 2F , 2E , 2C Expression is nuclear.
TS22: enamel knot Present 2F , 2E , 2C Expression is nuclear.
TS22: inner enamel epithelium Present 2F , 2E , 2C Expression is nuclear.
TS22: molar dental papilla Present 2F , 2E , 2C Expression is nuclear.
TS22: outer enamel epithelium Present 2F , 2E , 2C Expression is nuclear.
TS22: stellate reticulum Present 2F , 2E , 2C Expression is nuclear.
Specimen 3C: embryonic day 16.5 (more )
Note: Early bell stage of tooth development. Double labeled: green - Runx2; red - Fhl2 (assay MGI:7258371).
Structure Level Pattern Image Note
TS24: inner enamel epithelium Present 3C , 3F , 3E Expression is nuclear.
TS24: molar dental papilla Present 3C , 3F , 3E Expression is nuclear.
TS24: outer enamel epithelium Present 3C , 3F , 3E Expression is nuclear.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory