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Gene Expression Data
Assay Details
Assay
Reference: J:248980 Guo H, et al., Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258083
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: anti-Pecam1/CD31
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4A WT Vasculature: postnatal day 0 (more )
Note: Triple labeled: red - Pecam1 and Plvap (MECA32; assay MGI:7258085); green - Pdpn (assay MGI:7258078); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS27: lung vascular element lung microvascular endothelial cell Present Regionally restricted 4A WT (right) , 4A WT (middle) , 4A WT (left) Expression in endothelial cells in vasculature of distal lung. Dense capillary mesh with tight apposition of endothelial and epithelial cells.
Specimen 4A TNRC6c-/- Vasculature: postnatal day 0; Tnrc6cGt(IST11346C2)Tigm/Tnrc6cGt(IST11346C2)Tigm (more )
Note: Triple labeled: red - Pecam1 and Plvap (MECA32; assay MGI:7258085); green - Pdpn (assay MGI:7258078); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS27: lung vascular element lung microvascular endothelial cell Present Regionally restricted 4A TNRC6c-/- (left) , 4A TNRC6c-/- (right) , 4A TNRC6c-/- (middle) Lack of close physical association between endothelial and epithelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory