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Gene Expression Data
Assay Details
Assay
Reference: J:316478 Grzenda A, et al., Timing and expression of the angiopoietin-1-Tie-2 pathway in murine lung development and congenital diaphragmatic hernia. Dis Model Mech. 2013 Jan;6(1):106-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7256476
Gene symbol: Tek
Gene name: TEK receptor tyrosine kinase
Antibody: Anti-Tie-2
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 4C E12.5: embryonic day 12.5 (more )
Note: Double labeled: red - Tek; green - Cd34 (assay MGI:7256472).
Structure Level Pattern Image Note
TS20: lung vascular element Present Regionally restricted 4C E12.5 Tie-2 + CD34 (40x) Expression was detected in the endothelium of the developing vasculature during early development.
Specimen 4C E15.5: embryonic day 15.5 (more )
Note: Double labeled: red - Tek; green - Cd34 (assay MGI:7256472).
Structure Level Pattern Image Note
TS23: lung vascular element Present Regionally restricted 4C E15.5 Tie-2 + CD34 (40x) Expression was detected in the endothelium of the developing vasculature during early development.
Specimen 4C E18.5: embryonic day 18.5 (more )
Note: Double labeled: red - Tek; green - Cd34 (assay MGI:7256472).
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted 4C E18.5 Tie-2 + CD34 (40x) Expression shifted to the large vessels associated with central airways in late development although some expression remains in the mesenchyme.
Specimen 4C PN1: postnatal day 1 (more )
Note: Double labeled: red - Tek; green - Cd34 (assay MGI:7256472).
Structure Level Pattern Image Note
TS27: lung vascular element Present Regionally restricted 4C PN1 Tie-2 + CD34 (40x) Expression shifted to the large vessels associated with central airways in late development although some expression remains in the mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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