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Gene Expression Data
Assay Details
Assay
Reference: J:316478 Grzenda A, et al., Timing and expression of the angiopoietin-1-Tie-2 pathway in murine lung development and congenital diaphragmatic hernia. Dis Model Mech. 2013 Jan;6(1):106-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7256466
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: anti-alpha-SMA
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2C E12.5: embryonic day 12.5 (more )
Note: Double labeled: green - Acta2; red - Angpt1 (assay MGI:7256465).
Structure Level Pattern Image Note
TS20: bronchus Present Regionally restricted 2C E12.5 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was separate from Acta2 expression.
TS20: smooth muscle tissue Present Regionally restricted 2C E12.5 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was separate from Acta2 expression.
Specimen 2C E15.5: embryonic day 15.5 (more )
Note: Double labeled: green - Acta2; red - Angpt1 (assay MGI:7256465).
Structure Level Pattern Image Note
TS23: bronchus Present Regionally restricted 2C E15.5 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was separate from Acta2 expression.
TS23: smooth muscle tissue Present Regionally restricted 2C E15.5 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was separate from Acta2 expression.
Specimen 2C E18.5: embryonic day 18.5 (more )
Note: Double labeled: green - Acta2; red - Angpt1 (assay MGI:7256465).
Structure Level Pattern Image Note
TS26: bronchus Present Regionally restricted 2C E18.5 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was shifted to the primary, central airways.
TS26: respiratory system smooth muscle Present Regionally restricted 2C E18.5 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was shifted to the primary, central airways.
Specimen 2C PN1: postnatal day 1 (more )
Note: Double labeled: green - Acta2; red - Angpt1 (assay MGI:7256465).
Structure Level Pattern Image Note
TS27: bronchus Present Regionally restricted 2C PN1 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was shifted to the primary, central airways.
TS27: respiratory system smooth muscle Present Regionally restricted 2C PN1 Ang-1 + alpha-SMA (20x) Acta2 expression was detected in the smooth muscle-lined airways. Angpt1 expression was shifted to the primary, central airways.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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