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Dhx15em1Mmru
Endonuclease-mediated Allele Detail
Summary
Symbol: Dhx15em1Mmru
Name: DEAH-box helicase 15; endonuclease-mediated mutation 1, Manuel Morales-Ruiz
MGI ID: MGI:6856790
Gene: Dhx15  Location: Chr5:52307545-52347856 bp, - strand  Genetic Position: Chr5, 27.51 cM, cytoband C1
Alliance: Dhx15em1Mmru page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    TALEN-mediated genome-editing generated an 8 bp deletion in exon 2. (J:312413)
Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dhx15 Mutation:  38 strains or lines available
References
Original:  J:312413 Ribera J, et al., The loss of DHX15 impairs endothelial energy metabolism, lymphatic drainage and tumor metastasis in mice. Commun Biol. 2021 Oct 15;4(1):1192
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory