Pecam1 Immunohistochemistry Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:150211 Downes M, et al., Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation. Hum Mol Genet. 2009 Aug 1;18(15):2839-50
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6783426
Gene symbol:	Pecam1
Gene name:	platelet/endothelial cell adhesion molecule 1

Antibody:	anti-PECAM-1
Detection system:	Secondary antibody

Results

Specimen 6A WT: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		6A WT top , 6A WT bottom

Specimen 6A Ra^Op/Ra^Op: embryonic day 13.5; Sox18^Ra-Op/Sox18^Ra-Op (more

)

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		6A Ra^Op/Ra^Op bottom , 6A Ra^Op/Ra^Op top	The number of endothelial cells is increased in this mutant compared to wild-type.

Specimen 6B WT left: embryonic day 13.5 (more

)
Note: Double labeled: green - Pecam1; red - Cspg4 (assay MGI:6783425).

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		6B WT left
TS21: great vessel of heart	Present		6B WT left

Specimen 6B WT right: embryonic day 13.5 (more

)
Note: Double labeled: green - Pecam1; red - Cspg4 (assay MGI:6783425).

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		6B WT right

Specimen 6B Ra^Op/Ra^Op left: embryonic day 13.5; Sox18^Ra-Op/Sox18^Ra-Op (more

)
Note: Double labeled: green - Pecam1; red - Cspg4 (assay MGI:6783425).

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		6B Ra^Op/Ra^Op left

Specimen 6B Ra^Op/Ra^Op right: embryonic day 13.5; Sox18^Ra-Op/Sox18^Ra-Op (more

)
Note: Double labeled: green - Pecam1; red - Cspg4 (assay MGI:6783425).

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		6B Ra^Op/Ra^Op right

Specimen S1 WT: embryonic day 13.5 (more

)
Note: Double labeled: green - Pecam1; red - Cspg4 (assay MGI:6783425).

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		S1_WT PECAM-1 , S1_WT merge

Specimen S1 Ra^Op/Ra^Op left: embryonic day 13.5; Sox18^Ra-Op/Sox18^Ra-Op (more

)
Note: Double labeled: green - Pecam1; red - Cspg4 (assay MGI:6783425).

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		S1_Ra^Op/Ra^Op PECAM-1 left , S1_Ra^Op/Ra^Op Merge left

Specimen S1 Ra^Op/Ra^Op right: embryonic day 13.5; Sox18^Ra-Op/Sox18^Ra-Op (more

)
Note: Double labeled: green - Pecam1; red - Cspg4 (assay MGI:6783425).

Structure	Level	Pattern	Image	Note
TS21: blood vessel endothelium	Present		S1_Ra^Op/Ra^Op PECAM-1 right , S1_Ra^Op/Ra^Op Merge right

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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