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Gene Expression Data
Assay Details
Assay
Reference: J:310526 Williams Avram SK, et al., NMDA Receptor in Vasopressin 1b Neurons Is Not Required for Short-Term Social Memory, Object Memory or Aggression. Front Behav Neurosci. 2019;13:218
Assay type: RNA in situ
MGI Accession ID: MGI:6765933
Gene symbol: Grin1
Gene name: glutamate receptor, ionotropic, NMDA1 (zeta 1)
Probe: Grin1 probe (VB1-14161)
Probe preparation: Antisense labelled with Alexa Fluor DNA
Visualized with: Fluorescence
Assay notes: ViewRNA assay.
Results
Specimen 6A: postnatal adult; Grin1tm2Stl/? (more )
Note: Dorsal hippocampus. Wild type phenotype; either fl/fl or fl/+. Double labeled: red - Grin1; green - Avpr1b (assay MGI:6765926).
Structure Level Pattern Image Note
TS28: dentate gyrus Present 6A
TS28: fasciola cinereum Present 6A
TS28: hippocampus CA1 Present 6A
TS28: hippocampus CA2 Present 6A
TS28: hippocampus CA3 Present 6A
Specimen not shown: postnatal adult; Avpr1btm2.1(cre)Wsy/Avpr1b+, Grin1tm2Stl/Grin1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: dentate gyrus Present Expression levels are comparable to those seen in wild type.
TS28: fasciola cinereum Present Expression levels are comparable to those seen in wild type.
TS28: hippocampus CA1 Present Expression levels are comparable to those seen in wild type.
TS28: hippocampus CA2 Present Expression levels are comparable to those seen in wild type.
TS28: hippocampus CA3 Present Expression levels are comparable to those seen in wild type.
Specimen 6B: postnatal adult; Avpr1btm2.1(cre)Wsy/Avpr1b+, Grin1tm2Stl/Grin1tm2Stl (more )
Note: Conditional mutant. Dorsal hippocampus. Double labeled: red - Grin1; green - Avpr1b (assay MGI:6765926).
Structure Level Pattern Image Note
TS28: fasciola cinereum Present 6C , 6B Expression levels are significantly reduced in the mutant.
TS28: hippocampus CA2 Present 6D , 6B Expression levels are significantly reduced in the mutant.
TS28: dentate gyrus Present 6B Expression levels are comparable to those seen in wild type.
TS28: hippocampus CA1 Present 6B Expression levels are comparable to those seen in wild type.
TS28: hippocampus CA3 Present 6B Expression levels are comparable to those seen in wild type.
Specimen 6E: postnatal adult; Avpr1btm2.1(cre)Wsy/Avpr1b+, Grin1tm2Stl/Grin1tm2Stl (more )
Note: Conditional mutant. Dorsal hippocampus. Double labeled: red - Grin1; green - Gad1 (assay MGI:6765969).
Structure Level Pattern Image Note
TS28: fasciola cinereum Present Single cells 6E Expression is specifically lost from pyramidal cells.
Specimen 6F: postnatal adult; Avpr1btm2.1(cre)Wsy/Avpr1b+, Grin1tm2Stl/Grin1tm2Stl (more )
Note: Conditional mutant. Dorsal hippocampus. Double labeled: red - Grin1; green - Gad1 (assay MGI:6765969).
Structure Level Pattern Image Note
TS28: hippocampus CA2 Present Single cells 6F Expression is specifically lost from pyramidal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory