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Gene Expression Data
Assay Details
Assay
Reference: J:230349 Leslie EJ, et al., Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci. Am J Hum Genet. 2015 Mar 5;96(3):397-411
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695946
Gene symbol: Nog
Gene name: noggin
Antibody: Anti-Noggin antibody (ab16054)
Detection system: Alexa Fluor 555
Results
Specimen 5C: embryonic day 13.5 (more )
Note: Double labeled: red - Nog; green - Trp63 (assay MGI:6695947).
Structure Level Pattern Image Note
TS21: mandible Present Regionally restricted 5C Expression in periderm, basal cell layer and underlying mesenchyme.
TS21: palatal shelf Present Regionally restricted 5C Expression in periderm, basal cell layer and underlying mesenchyme.
TS21: tongue Present Regionally restricted 5C Expression in periderm, basal cell layer and underlying mesenchyme.
Specimen 5D: embryonic day 13.5 (more )
Note: Double labeled: red - Nog; green - Trp63 (assay MGI:6695947).
Structure Level Pattern Image Note
TS21: palatal shelf epithelium Present Regionally restricted 5D Expression primarily in palatal epithelium, in both basal and periderm layers.
TS21: periderm Present Regionally restricted 5D Expression primarily in palatal epithelium, in both basal and periderm layers.
TS21: palatal shelf mesenchyme Present 5D Expression also detectable in mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory