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Gene Expression Data
Assay Details
Assay
Reference: J:230349 Leslie EJ, et al., Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci. Am J Hum Genet. 2015 Mar 5;96(3):397-411
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695944
Gene symbol: Ntn1
Gene name: netrin 1
Antibody: Netrin-1 antibody
Detection system: Alexa Fluor 555
Results
Specimen 4F: embryonic day 13.5 (more )
Note: Double labeled: red - Ntn1; green - Trp63 (assay MGI:6695947).
Structure Level Pattern Image Note
TS21: mandible mesenchyme Present Regionally restricted 4F Expression localized to both mesenchyme and basement membrane.
TS21: tongue mesenchyme Present Regionally restricted 4F Expression localized to both mesenchyme and basement membrane.
TS21: palatal shelf mesenchyme Strong Regionally restricted 4F High level expression especially along basement membrane of palatal shelves.
Specimen 4G: embryonic day 13.5 (more )
Note: Double labeled: red - Ntn1; green - Trp63 (assay MGI:6695947).
Structure Level Pattern Image Note
TS21: palatal shelf Present Regionally restricted 4G Highest level of expression along presumptive medial edges and oral sides of palatal shelves.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory