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Gene Expression Data
Assay Details
Assay
Reference: J:250135 Ding M, et al., Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay. Front Mol Neurosci. 2017;10:121
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6515780
Gene symbol: Calb1
Gene name: calbindin 1
Antibody: anti-calbindin D-28K (#300)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 4A WT: postnatal month 6 (more )
Note: Double labeled: green - Calb1; red - Ankfy1 (assay MGI:6515781).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4A WT Calbindin , 4A WT Merged
Specimen 4A Ankfy1/+: postnatal month 6; Ankfy1Gt(RRE069)Byg/Ankfy1+ (more )
Note: Double labeled: green - Calb1; red - Ankfy1 (assay MGI:6515781).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 4A Ankfy1/+ Merged , 4A Ankfy1/+ Calbindin The Ankfy1/+ mice exhibited severe Purkinje cell loss.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory