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Gene Expression Data
Assay Details
Assay
Reference: J:299732 Zhou X, et al., Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. Nat Commun. 2020 Aug 13;11(1):4063
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6514833
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-ISL1 (ab20670)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6c E12.5: embryonic day 12.5 (more )
Note: Double labeled: green - Isl1; red - Nr5a1 (assay MGI:6514841).
Structure Level Pattern Image Note
TS20: hypothalamus mantle layer Present Regionally restricted 6c E12.5 Merge , 6c E12.5 ISL1 There is differential expression from the rostral to caudal hypothalamus across the dorsal-ventral mantle zone.
Specimen 6c E14.5: embryonic day 14.5 (more )
Note: Double labeled: green - Isl1; red - Nr5a1 (assay MGI:6514841).
Structure Level Pattern Image Note
TS22: hypothalamus mantle layer Present Regionally restricted 6c E14.5 Merge , 6c E14.5 ISL1 Expressing cells accumulated in the ventro-lateral mantle domain, with scattered labeling in the medial region.
Specimen 6c E16.5: embryonic day 16.5 (more )
Note: Double labeled: green - Isl1; red - Nr5a1 (assay MGI:6514841).
Structure Level Pattern Image Note
TS24: hypothalamus mantle layer Present 6c E16.5 ISL1 , 6c E16.5 Merge
Specimen S6b anterior E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus mantle layer Present Regionally restricted S6b E12.5 anterior There is differential expression from the rostral to caudal hypothalamus across the dorsal-ventral mantle zone.
Specimen S6b tuberal E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus mantle layer Present Regionally restricted S6b E12.5 tuberal There is differential expression from the rostral to caudal hypothalamus across the dorsal-ventral mantle zone.
Specimen S6b posterior E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hypothalamus mantle layer Present Regionally restricted S6b E12.5 posterior There is differential expression from the rostral to caudal hypothalamus across the dorsal-ventral mantle zone.
Specimen S6b anterior E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hypothalamus mantle layer Present Regionally restricted S6b E14.5 anterior Expressing cells accumulated in the ventro-lateral mantle domain, with scattered labeling in the medial region.
Specimen S6b tuberal E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hypothalamus mantle layer Present Regionally restricted S6b E14.5 tuberal Expressing cells accumulated in the ventro-lateral mantle domain, with scattered labeling in the medial region.
Specimen S6b posterior E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hypothalamus mantle layer Present Regionally restricted S6b E14.5 posterior Expressing cells accumulated in the ventro-lateral mantle domain, with scattered labeling in the medial region.
Specimen S6b anterior E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hypothalamus mantle layer Present S6b E16.5 anterior
Specimen S6b tuberal E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hypothalamus mantle layer Present S6b E16.5 tuberal
Specimen S6b posterior E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: hypothalamus mantle layer Present S6b E16.5 posterior
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory