Six2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:296648 Lindstrom NO, et al., Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. J Am Soc Nephrol. 2018 Mar;29(3):806-824
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6505891
Gene symbol:	Six2
Gene name:	sine oculis-related homeobox 2

Antibody:	anti-Six2 (MBS610128)
Detection system:	Secondary antibody coupled to Alexa Fluor
Assay notes:	The authors used two Six2 antibodies; it is possible that MGI:6505815 was used to obtain some or all of these data.

Results

Specimen 2A: embryonic day 15.5 (more

)
Note: Triple labeled: green - Six2; red - Cited1 (assay MGI:6505894); blue - Krt8 (assay MGI:6505890)

Structure	Level	Pattern	Image	Note
TS23: cap mesenchyme	Present	Regionally restricted	2A	Expression is seen in nephron progenitor cells.
TS23: pretubular aggregate	Present		2A

Specimen 2G: embryonic day 15.5 (more

)
Note: Triple labeled: red- Six2; green - Foxd1 (assay MGI:6505895); blue - Krt8 (assay MGI:6505890)

Structure	Level	Pattern	Image	Note
TS23: cap mesenchyme	Present	Regionally restricted	2G	Expression is seen in nephron progenitor cells.
TS23: pretubular aggregate	Present		2G

Specimen S1B: embryonic day 15.5 (more

)
Note: Triple labeled: red - Six2; green - Meis1 (assay MGI:6505893); blue - Krt8 (assay MGI:6505890)

Structure	Level	Pattern	Image	Note
TS23: cap mesenchyme	Present	Regionally restricted	S1B left	Expression is seen in nephron progenitor cells.
TS23: pretubular aggregate	Present		S1B left

Specimen S1C: postnatal day 2 (more

)
Note: Triple labeled: red - Six2; green - Meis1 (assay MGI:6505893); blue - Krt8 (assay MGI:6505890)

Structure	Level	Pattern	Image	Note
TS27: cap mesenchyme	Present	Regionally restricted	S1C left	Expression is seen in nephron progenitor cells.
TS27: renal vesicle	Present		S1C left

Specimen S1F: embryonic day 15.5 (more

)
Note: Multi-labeled: green - Six2; red - Foxd1 (assay MGI:6505895); blue - Krt8 (assay MGI:6505890) and Krt18 (assay MGI:6506269)

Structure	Level	Pattern	Image	Note
TS23: cap mesenchyme	Present	Regionally restricted	S1F	Expression is seen in nephron progenitor cells.

Specimen S1G: postnatal day 2 (more

)
Note: Multi-labeled: green - Six2; red - Foxd1 (assay MGI:6505895); blue - Krt8 (assay MGI:6505890) and Krt18 (assay MGI:6506269)

Structure	Level	Pattern	Image	Note
TS27: cap mesenchyme	Present	Regionally restricted	S1G	Expression is seen in nephron progenitor cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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