About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:273779 Lindstrom NO, et al., Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. J Am Soc Nephrol. 2018 Mar;29(3):785-805
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6505840
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2 (MBS610128)
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: The authors used two Six2 antibodies; it is possible that MGI:6505815 was used to obtain some or all of these data.
Results
Specimen 4D: embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:6505838); blue - phospho-histone 3.
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted 4D Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen 4E: postnatal day 2 (more )
Note: Triple labeled: red - Six2; green - Krt8 (assay MGI:6505838); blue - phospho-histone 3.
Structure Level Pattern Image Note
TS27: cap mesenchyme Present Regionally restricted 4E Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen S2C: embryonic day 15.5 (more )
Note: Triple labeled: red - Six2; green - Meis1 (assay MGI:6505839); blue - Krt8 (assay MGI:6505838)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted S2C Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen S3B - left: embryonic day 15.5 (more )
Note: Double labeled: red - Six2; gray - Krt8 (assay MGI:6505838)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present Regionally restricted S3B left Expression is seen in nephron progenitor cells beneath the kidney capsule.
Specimen S3B - right: postnatal day 2 (more )
Note: Double labeled: red - Six2; gray - Krt8 (assay MGI:6505838)
Structure Level Pattern Image Note
TS27: cap mesenchyme Present Regionally restricted S3B right Expression is seen in nephron progenitor cells beneath the kidney capsule.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory