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Gene Expression Data
Assay Details
Assay
Reference: J:36690 Buck CA, et al., Expression patterns of adhesion receptors in the developing mouse lung: functional implications. Cell Adhes Commun. 1996 Aug;4(2):69-87
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6504907
Gene symbol: Thbd
Gene name: thrombomodulin
Antibody: anti-thrombomodulin
Detection system: Secondary antibody coupled to fluorescein
Assay notes: Embryos were staged according to Kaufman, M.H. (1992) The Atlas of Mouse Development. Academic Press, London.
Results
Specimen 6B: embryonic day 11.5 (more )
Note: Double labeled: green - Thbd; red - F8 (assay MGI:6504916).
Structure Level Pattern Image Note
TS19: lung epithelium Strong Regionally restricted 6B Expression is in the epithelium of the budding airways.
TS19: lung mesenchyme Weak 6B
TS19: lobar bronchus epithelium Absent 6B
Specimen 6D: embryonic day 12.0 (more )
Note: Double labeled: green - Thbd; red - F8 (assay MGI:6504916).
Structure Level Pattern Image Note
TS20: lung mesenchyme Present Regionally restricted 6D Expression is in regions corresponding to those rich in peri-bronchial smooth muscle cells.
TS20: lobar bronchus epithelium Present Regionally restricted 6D Expression is at the budding tips of the branching bronchi and is absent in the airway epithelium.
Specimen 6F: embryonic day 16.0 (more )
Note: Double labeled: green - Thbd; red - laminin.
Structure Level Pattern Image Note
TS24: lung mesenchyme Present Regionally restricted 6F Expression is in perivascular and peribronchial regions rich in smooth muscle cells.
TS24: lung vascular element Present Regionally restricted 6F Expression is in the endothelium.
TS24: bronchiole epithelium Absent 6F
TS24: lobar bronchus epithelium Absent 6F
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: lung alveolus Present
TS28: lobar bronchus Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory