Gene Expression Data
Assay Details
Assay
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Reference:
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J:100909
Vasyutina E, et al., CXCR4 and Gab1 cooperate to control the development of migrating muscle progenitor cells. Genes Dev. 2005 Sep 15;19(18):2187-98
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6491875
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Gene symbol:
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Cxcr4
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Gene name:
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C-X-C motif chemokine receptor 4
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Results
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Specimen
2G:
embryonic day 10.25
(more )
Note: Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
Specimen
2G:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.25
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
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Specimen
3A:
embryonic day 10.25
(more )
Note: Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
Specimen
3A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.25
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: dermomyotome |
Absent |
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3A
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No expression in ventral dermomyotomal lip, delaminating Lbx1-expressing cells or myotome. Co-expression with Lbx1 only after migrating progenitors cells have moved away from the dermomyotome.
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TS17: myotome |
Absent |
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3A
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No expression in ventral dermomyotomal lip, delaminating Lbx1-expressing cells or myotome. Co-expression with Lbx1 only after migrating progenitors cells have moved away from the dermomyotome.
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TS17: forelimb bud mesenchyme |
Present |
Regionally restricted |
3A
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Co-expression with Lbx1 in muscle masses. All Cxcr4-expressing cells in premuscle masses also expressing Lbx1. Expression in subpopulation of Lbx1-expressing cells located close to ectoderm.
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TS17: forelimb bud |
Present |
Regionally restricted |
3A
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Expression in limb endothelial cells.
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Specimen
3B:
embryonic day 10.75
(more )
Note: Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
Specimen
3B:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.75
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: forelimb bud mesenchyme |
Present |
Regionally restricted |
3B
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Co-expression with Lbx1 in muscle masses. All Cxcr4-expressing cells in premuscle masses also expressing Lbx1. Expression in subpopulation of Lbx1-expressing cells located close to ectoderm. Significant number of Lbx1-expressing cells remain negative for Cxcr4 expression.
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Specimen
3C:
embryonic day 11.25
(more )
Note: Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
Specimen
3C:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.25
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
|
Note:
|
Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: forelimb bud mesenchyme |
Present |
Regionally restricted |
3C
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Co-expression with Lbx1 in muscle masses. All Cxcr4-expressing cells in premuscle masses also expressing Lbx1. Expression in subpopulation of Lbx1-expressing cells located close to ectoderm. Significant number of Lbx1-expressing cells remain negative for Cxcr4 expression.
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Specimen
3D:
embryonic day 10.25
(more )
Note: Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
Specimen
3D:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.25
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
|
Note:
|
Double labeled: red - Cxcr4; green - Lbx1 (assay MGI:6491874).
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: forelimb bud mesenchyme |
Present |
Regionally restricted |
3D
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Co-expression with Lbx1 in muscle masses. All Cxcr4-expressing cells in premuscle masses also expressing Lbx1. Expression in subpopulation of Lbx1-expressing cells located close to ectoderm.
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Specimen
3E:
embryonic day 10.25
(more )
Note: Double labeled: red - Cxcr4; green - Myod1 (assay MGI:6491876).
Specimen
3E:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.25
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Cxcr4; green - Myod1 (assay MGI:6491876).
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Specimen
not shown:
embryonic day 10.5
(more )
Specimen
not shown:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS17: forelimb bud mesenchyme |
Present |
Regionally restricted |
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Authors state Cxcr4-expressing and Myod1-expressing cell populations are distinct at E10.25, E10.5 and E11.25.
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Specimen
3F:
embryonic day 11.25
(more )
Note: Double labeled: red - Cxcr4; green - Myod1 (assay MGI:6491876).
Specimen
3F:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.25
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Note:
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Double labeled: red - Cxcr4; green - Myod1 (assay MGI:6491876).
|
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