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Gene Expression Data
Assay Details
Assay
Reference: J:208048 Tortoriello G, et al., Miswiring the brain: Delta9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway. EMBO J. 2014 Apr 1;33(7):668-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6491611
Gene symbol: Stmn2
Gene name: stathmin-like 2
Antibody: anti-SCG10/Stmn2
Detection system: Secondary antibody
Assay notes: To maximize epitope coverage, the authors used a cocktail of antibodies (MGI:6491601 and MGI:6491603) for their experiments.
Results
Specimen 3C: embryonic day 14.5 (more )
Note: Double labeled: green - Stmn2; red - Cnr1 (assay MGI:6491612)
Structure Level Pattern Image Note
TS22: telencephalon Present 3C Expression is enriched in axonal pathways and accumulates in growth cone-like structures traversing the pallio-subpallial boundary.
Specimen 3D: embryonic day 18.5 (more )
Note: Triple labeled: green - Stmn2; red - Cnr1 (assay MGI:6491612); blue - L1cam (assay MGI:6491618)
Structure Level Pattern Image Note
TS26: cortical plate Present 3D merge , 3D green
TS26: cerebral cortex intermediate zone Present 3D merge , 3D green Expression is seen in corticofugal axons.
Specimen 3D1: embryonic day 18.5 (more )
Note: Double labeled: green - Stmn2; red - Dpysl2 (CRMP-2; assay MGI:6491620)
Structure Level Pattern Image Note
TS26: cortical plate Present 3D1 green , 3D1 merge
Specimen 3D2: embryonic day 18.5 (more )
Note: Double labeled: green - Stmn2; red - Cnr1 (assay MGI:6491612)
Structure Level Pattern Image Note
TS26: cerebral cortex intermediate zone Present 3D2 Expression is seen in corticofugal axons.
Specimen 6D right: postnatal day 0 (more )
Note: Double labeled: green - Stmn2; blue - Cnr1 (assay MGI:6491612)
Structure Level Pattern Image Note
TS27: cerebral cortex Present 6D right Expression is seen in corticofugal axons.
Specimen 6D1 right: postnatal day 0; Mapk8tm1Flv/Mapk8tm1Flv (more )
Note: Double labeled: green - Stmn2; blue - Cnr1 (assay MGI:6491612)
Structure Level Pattern Image Note
TS27: cerebral cortex Present 6D1 right Expression is seen in corticofugal axons; expression levels are increased in mutants relative to wild type.
Specimen S2C: embryonic day 14.5 (more )
Note: Double labeled: green - Stmn2; red - Cnr1 (assay MGI:6491612)
Structure Level Pattern Image Note
TS22: hippocampus Present S2C right , S2C left Expression is seen in migrating neurons.
Specimen S2C1: embryonic day 18.5 (more )
Note: Double labeled: green - Stmn2; red - Cnr1 (assay MGI:6491612)
Structure Level Pattern Image Note
TS26: hippocampus Present S2C1 lower , S2C1 upper Expression is seen in axons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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