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Gene Expression Data
Assay Details
Assay
Reference: J:193583 Cai Y, et al., Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons. J Comp Neurol. 2013 Feb 1;521(2):479-97
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6490541
Gene symbol: Sst
Gene name: somatostatin
Antibody: Anti-Somatostatin (D-20; sc-7819)
Detection system: Secondary antibody
Results
Specimen 4A/B/C/D/E: postnatal day 28 (more )
Note: Double labeled: green - Sst; magenta - Nr2f2 (assay MGI:6490533).
Structure Level Pattern Image Note
TS28: cortical layer V Present 4A , 4E , 4D , 4B , 4C Nr2r2+Sst+ interneurons were mainly in layer V of the motor and somatosensory cortex.
TS28: cortical layer IV Present 4A A very small number of Nr2r2+Sst+ interneurons were found.
TS28: cortical layer VI Present 4A A very small number of Nr2r2+Sst+ interneurons were found.

Specimen 4F/G: postnatal day 28 (more )
Note: Double labeled: green - Sst; magenta - Nr2f2 (assay MGI:6490533).
Structure Level Pattern Image Note
TS28: cortical layer V Present 4F , 4G Nr2r2+Sst+ interneurons were mainly in layer V of the visual cortex.
TS28: cortical layer IV Present 4F , 4G A very small number of Nr2r2+Sst+ interneurons were found.
TS28: cortical layer VI Present 4F , 4G A very small number of Nr2r2+Sst+ interneurons were found.

Specimen 4H/J: postnatal day 28 (more )
Note: Triple labeled: green - Sst; magenta - Nr2f2 (assay MGI:6490533); blue - Calb2 (assay MGI:6490544).
Structure Level Pattern Image Note
TS28: cortical layer V Present 4J , 4H Nr2r2+Sst+ interneurons were mainly in layer V of the visual cortex.

Specimen not shown: postnatal week 14 (more )
Note: aged mice (>14 months)
Structure Level Pattern Image Note
TS28: cortical layer V Present Nr2r2+Sst+ interneurons were mainly in layer V of the visual cortex. No Nr2r2+Sst+Calb2+ neocortical interneurons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory