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Klrc1em2Lumc
Endonuclease-mediated Allele Detail
Summary
Symbol: Klrc1em2Lumc
Name: killer cell lectin-like receptor subfamily C, member 1; endonuclease-mediated mutation 2, Leiden University Medical Centre
MGI ID: MGI:6473464
Gene: Klrc1  Location: Chr6:129642978-129655936 bp, - strand  Genetic Position: Chr6, 63.44 cM, cytoband G1-2
Alliance: Klrc1em2Lumc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsMouse zygotes were electroporated with two CRISPR/Cas9 RNP complexes, one using sgRNA ATCTCAGTAAAGAATCTCCA targeting intron 2, the other sgRNA CTACAGGTTGAAAACTGCTG targeting intron 4. Founder mice with a deletion of exon 3 and 4 were identified. (J:341640, J:349488)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Klrc1 Mutation:  11 strains or lines available
References
Original:  J:341640 Leiden University, Leiden University Direct Data Submission. MGI Direct Data Submission. 2023;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/05/2025
MGI 6.24
The Jackson Laboratory