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Gene Expression Data
Assay Details
Assay
Reference: J:262122 Gigante ED, et al., Hypomorphic Smo mutant with inefficient ciliary enrichment disrupts the highest level of vertebrate Hedgehog response. Dev Biol. 2018 May 15;437(2):152-162
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6469353
Gene symbol: Foxa2
Gene name: forkhead box A2
Antibody: anti-FoxA2/HNF3beta (D56D6; #8186)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 3E: embryonic day 10.5; Smocbb/Smo+ (more )
Note: Triple labeled: red - Foxa2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS17: neural tube floor plate Present 3E
Specimen 3F: embryonic day 10.5; Smocbb/Smocbb (more )
Note: Triple labeled: red - Foxa2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS17: neural tube floor plate Weak 3F Fewer Foxa2-expressing cells; some co-expressing Nkx2.2.
Specimen 3I: embryonic day 11.5; Smocbb/Smo+ (more )
Note: Triple labeled: red - Foxa2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS19: neural tube floor plate Present Regionally restricted 3I Expression in columnar cells in floor plate adjacent to Nkx2.2- and Olig2-expressing cells.
Specimen 3J: embryonic day 11.5; Smocbb/Smocbb (more )
Note: Triple labeled: red - Foxa2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS19: neural tube floor plate Weak Regionally restricted 3J Few columnar Foxa2-expressing cells at midline. No co-expression with Nkx2.2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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