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Gene Expression Data
Assay Details
Assay
Reference: J:177843 Hillman RT, et al., Neuropilins are positive regulators of Hedgehog signal transduction. Genes Dev. 2011 Nov 15;25(22):2333-46
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6466565
Gene symbol: Nrp1
Gene name: neuropilin 1
Antibody: anti-Nrp1
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3A: embryonic day 8.5 (more )
Note: Triple labeled: red - Nrp1; green - Smo (assay MGI:6466564); blue - Tubulin.
Structure Level Pattern Image Note
TS13: yolk sac mesenchyme Present 3B Nrp1 , 3B , 3A
Specimen 3C: embryonic day 8.5 (more )
Note: Triple labeled: red - Nrp1; green - Smo (assay MGI:6466564); blue - Tubulin.
Structure Level Pattern Image Note
TS13: paraxial mesenchyme Present 3D , 3D Nrp1 , 3C
Specimen 3E: embryonic day 17.5 (more )
Note: Double labeled: red - Nrp1; green - Nrp2 (assay MGI:6466566).
Structure Level Pattern Image Note
TS25: hair follicle dermal papilla Present Regionally restricted 3E Nrp1 , 3E Merge Expression was most abundant in the distal dermal condensate.
Specimen S5A top: embryonic day 17.5 (more )
Note: Early-stage (stage 2) hair follicles. Double labeled: green - Nrp1; red - Ngfr (assay MGI:6466567).
Structure Level Pattern Image Note
TS25: blood vessel endothelium Present S5A top left , S5A top right
TS25: hair follicle dermal papilla Present S5A top left , S5A top right
Specimen S5A bottom: embryonic day 17.5 (more )
Note: Early-stage (stage 2) hair follicles. Triple labeled: green - Nrp1; red - Pecam1 (assay MGI:6466568); blue - Ngfr (assay MGI:6466567).
Structure Level Pattern Image Note
TS25: blood vessel endothelium Present S5A bottom left , S5A bottom right
TS25: hair follicle dermal papilla Present S5A bottom left , S5A bottom right
Specimen S5B: embryonic day 17.5 (more )
Note: Midstage (stage 4) hair follicles. Triple labeled: green - Nrp1; red - Pecam1 (assay MGI:6466568); blue - Ngfr (assay MGI:6466567).
Structure Level Pattern Image Note
TS25: blood vessel endothelium Present S5B left , S5B right
TS25: hair epidermal placode Present S5B left , S5B right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory