Ins1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:155058 Zhang H, et al., Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation. Mech Dev. 2009 Dec;126(11-12):958-73
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6458840
Gene symbol:	Ins1
Gene name:	insulin I

Antibody:

anti-insulin

Results

2C ©

Specimen 2C: embryonic day 15.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: red - Ins1 and Ins2; green - HNF6 (Onecut1 assay MGI:6458834).

Structure	Level	Pattern	Image	Note
TS23: endocrine pancreas	Present	Regionally restricted	2C

2F ©

Specimen 2F: postnatal day 1; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: red - Ins1 and Ins2; green - HNF6 (Onecut1 assay MGI:6458834).

Structure	Level	Pattern	Image	Note
TS27: endocrine pancreas	Present	Regionally restricted	2F

Specimen E18.5: embryonic day 18.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: endocrine pancreas	Weak	Regionally restricted		Number of beta cells was reduced at E18.5.

S2A* ©

Specimen S2A*: postnatal day 2; Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺, Tg(Neurog3-cre)C1Able/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: endocrine pancreas	Present		S2A*

S2B* ©

Specimen S2B*: postnatal day 2; Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺, Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Neurog3-cre)C1Able/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: endocrine pancreas	Present		S2B*

6D ©

Specimen 6D: postnatal adult; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: green - Ins1 and Ins2; red - cytokeratin.

Structure	Level	Pattern	Image	Note
TS28: endocrine pancreas	Present		6D

6E ©

Specimen 6E: postnatal adult; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - cytokeratin.

Structure	Level	Pattern	Image	Note
TS28: pancreas	Present	Regionally restricted	6E	Expressing cells abnormally located within multilayered epithelium.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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