Map1lc3b Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:270838 Wiederstein JL, et al., Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown. Cell Rep. 2018 May 1;23(5):1342-1356
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6458592
Gene symbol:	Map1lc3b
Gene name:	microtubule-associated protein 1 light chain 3 beta

Antibody:	anti-LC3 (#2775)
Detection system:	Alexa Fluor

Results

Specimen S3C LC3 wild-type: postnatal adult (more

)

Structure	Level	Pattern	Image	Note
TS28: soleus	Present		S3C LC3 wild type

Specimen S3C LC3 Mettl21c -/-: postnatal adult; Mettl21c^tm1.1Krug/Mettl21c^tm1.1Krug (more

)

Structure	Level	Pattern	Image	Note
TS28: soleus	Strong		S3C LC3 Mettl21c -/-	Authors report upregulation of expression.

S3D LC3 ©

S3D Merge ©

Specimen S3D LC3: postnatal adult (more

)
Note: Double labeled: red - Map1lc3a (LC3); blue - Myh7 (assay MGI:6458580).

Structure	Level	Pattern	Image	Note
TS28: soleus	Present	Regionally restricted	S3D LC3 , S3D Merge	Expression in slow muscle fibers.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23