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Gene Expression Data
Assay Details
Assay
Reference: J:262744 Shetty R, et al., Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning. Sci Rep. 2018 Apr 4;8(1):5632
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6456209
Gene symbol: Ly76
Gene name: lymphocyte antigen 76
Antibody: clone TER-119
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1h TS Control: embryonic day 9.5 (more )
Note: Double labeled: red - Ly76; green - Acta2 (assay MGI:6456236).
Structure Level Pattern Image Note
TS15: blood Present 1h upper left

Specimen 1h TS -/-: embryonic day 9.5; Bcas3tm1.1Msin/Bcas3tm1.1Msin (more )
Note: Double labeled: red - Ly76; green - Acta2 (assay MGI:6456236).
Structure Level Pattern Image Note
TS15: blood Present 1h upper right Collapsed, smaller heart chambers and a fused atrio-ventricular canal were seen.

Specimen 2d control embryonic: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood Present 2d left

Specimen 2d control placenta: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood Present 2d left

Specimen 2d -/- embryonic: embryonic day 9.5; Bcas3tm1.1Msin/Bcas3tm1.1Msin (more )
Structure Level Pattern Image Note
TS15: blood Trace 2d right Fetal blood vessels could not invade into the placenta, and fewer positive fetal erythrocytes as compared to controls.

Specimen 2d -/- placenta: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood Present 2d right

Specimen 6c Control embryonic: embryonic day 10.5; Bcas3tm1Msin/? (more )
Note: The genotype of the control was not specified, either flox/flox, or flox/+.
Structure Level Pattern Image Note
TS17: blood Present 6c left

Specimen 6c Control placenta: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood Present 6c left

Specimen 6c CKO embryonic: embryonic day 10.5; Bcas3tm1Msin/Bcas3tm1Msin, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: blood Present 6c right Comparable to the control.

Specimen 6c CKO placenta: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood Present 6c right Comparable to the control.

Specimen 6e Control embryonic: embryonic day 11.5; Bcas3tm1Msin/? (more )
Note: The genotype of the control was not specified, either flox/flox, or flox/+.
Structure Level Pattern Image Note
TS19: blood Present 6e left

Specimen 6e Control placenta: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood Present 6e left

Specimen 6e CKO embryonic: embryonic day 11.5; Bcas3tm1Msin/Bcas3tm1Msin, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: blood Present 6e right Reduced fetal vessel invasion, although not as severely as in the global knock-out.

Specimen 6e CKO placenta: postnatal adult (more )
Structure Level Pattern Image Note
TS28: blood Present 6e right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory