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Henmt1em1Pdz
Endonuclease-mediated Allele Detail
Summary
Symbol: Henmt1em1Pdz
Name: HEN1 methyltransferase homolog 1 (Arabidopsis); endonuclease-mediated mutation 1, Phillip Zamore
MGI ID: MGI:6452642
Gene: Henmt1  Location: Chr3:108847375-108868090 bp, + strand  Genetic Position: Chr3, 47.99 cM, cytoband G1
Alliance: Henmt1em1Pdz page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Intragenic deletion
 
Mutation details: CRISPR-mediated replacement of 21 bp region of exon 4 results in 12 nucleotide substitutions producing 7 missense mutations in catalytically active region. (J:316804)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Henmt1 Mutation:  15 strains or lines available
References
Original:  J:316804 Gainetdinov I, et al., Terminal modification, sequence, length, and PIWI-protein identity determine piRNA stability. Mol Cell. 2021 Dec 2;81(23):4826-4842.e8
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory