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Gene Expression Data
Assay Details
Assay
Reference: J:148710 Ezhkova E, et al., Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell. 2009 Mar 20;136(6):1122-35
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6450685
Gene symbol: Flg
Gene name: filaggrin
Results
Specimen 4C WT: postnatal day 0 (more )
Note: Double labeled: red - Flg; green - Krt5 (assay MGI:6450683).
Structure Level Pattern Image Note
TS27: epidermis granular layer Present 4C WT
Specimen 4C cKO: postnatal day 0; Ezh2tm1Tara/Ezh2tm1Tara, Tg(KRT14-cre)1Efu/0 (more )
Note: Conditional mutant. Double labeled: red - Flg; green - Krt5 (assay MGI:6450683).
Structure Level Pattern Image Note
TS27: epidermis granular layer Present Regionally restricted 4C cKO Authors report expansion of granular marker expression.
Specimen 4F WT: embryonic day 16.0 (more )
Note: Double labeled: red - Flg; green - Krt5 (assay MGI:6450683).
Structure Level Pattern Image Note
TS24: epidermis Present Regionally restricted 4F WT Expression in granular layer.
Specimen 4F cKO: embryonic day 16.0; Ezh2tm1Tara/Ezh2tm1Tara, Tg(KRT14-cre)1Efu/0 (more )
Note: Conditional mutant. Double labeled: red - Flg; green - Krt5 (assay MGI:6450683).
Structure Level Pattern Image Note
TS24: epidermis Present Regionally restricted 4F cKO Authors report expansion of granular marker expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory