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Gene Expression Data
Assay Details
Assay
Reference: J:77320 Wilson ME, et al., Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas. Mech Dev. 2002 Jul;115(1-2):171-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441727
Gene symbol: Pou3f4
Gene name: POU domain, class 3, transcription factor 4
Antibody: brn-4 antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 5 e10.5 brn-4: embryonic day 10.5 (more )
Note: Double labeled: green - Pou3f4; red - Gcg (assay MGI:6441719).
Structure Level Pattern Image Note
TS17: pancreas primordium Present Regionally restricted 5_e10.5 Expression detectable in proglucagon-expressing alpha cells by E10.5.
Specimen 5 e15.5 (left) brn-4: embryonic day 15.5 (more )
Note: Double labeled: green - Pou3f4; red - Ins1 (assay MGI:6441724) and Ins2 (assay MGI:6441725).
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted 5_e15.5 brn-4/insulin No expression in insulin-expressing beta cells.
Specimen 5 e15.5 (right) brn-4: embryonic day 15.5 (more )
Note: Double labeled: green - Pou3f4; red - Gcg (assay MGI:6441719).
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted 5_e15.5 brn-4/glucagon Expression in most proglucagon-expressing alpha cells and in a scattering of other non-beta cells.
Specimen 5 e18.5 brn-4: embryonic day 18.5 (more )
Note: Double labeled: green - Pou3f4; red - Gcg (assay MGI:6441719).
Structure Level Pattern Image Note
TS26: pancreas Present Regionally restricted 5_e18.5 Expression in most proglucagon-expressing alpha cells and in a scattering of other non-beta cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory