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Gpr35tm1.1Niess
Targeted Allele Detail
Summary
Symbol: Gpr35tm1.1Niess
Name: G protein-coupled receptor 35; targeted mutation 1.1, Jan Hendrik Niess
MGI ID: MGI:6436879
Synonyms: Gpr35-IRES-tdTomato
Gene: Gpr35  Location: Chr1:92878587-92914113 bp, + strand  Genetic Position: Chr1, 46.65 cM, cytoband D
Alliance: Gpr35tm1.1Niess page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:300275
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsAn IRES and tdTomato repoter gene were inserted downstream of the stop codon in exon 2. Flp-mediated recombination removed the selection cassette inserted upstream of exon 2. (J:300275)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr35 Mutation:  30 strains or lines available
References
Original:  J:300275 Kaya B, et al., Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1(+) Macrophages Regulates Intestinal Homeostasis. Cell Rep. 2020 Aug 4;32(5):107979
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory