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Gene Expression Data
Assay Details
Assay
Reference: J:173839 Bertrand N, et al., Hox genes define distinct progenitor sub-domains within the second heart field. Dev Biol. 2011 May 15;353(2):266-74
Assay type: RNA in situ
MGI Accession ID: MGI:6430434
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: Isl1 probe36
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1C: embryonic day 7.75 (more )
Note: Double labeled: blue - Isl1; orange - Hoxb1 (assay MGI:6430416).
Structure Level Pattern Image Note
TS12: secondary heart field Present 1C Expression marks second heart field.

Specimen 1F: embryonic day 7.75 (more )
Note: Double labeled: blue - Isl1; orange - Hoxa1 (assay MGI:6430418).
Structure Level Pattern Image Note
TS12: secondary heart field Present 1F Expression marks second heart field.

Specimen 1I: embryonic day 7.75 (more )
Structure Level Pattern Image Note
TS12: secondary heart field Present 1I Expression marks second heart field.

Specimen 1I inset: embryonic day 7.75 (more )
Structure Level Pattern Image Note
TS12: secondary heart field Present 1I inset Expression marks second heart field.

Specimen S2A: embryonic day 8.5 (more )
Note: Double labeled: blue - Isl1; orange - Hoxb1 (assay MGI:6430416).
Structure Level Pattern Image Note
TS13: secondary heart field Present S2A

Specimen S2A': embryonic day 8.5 (more )
Note: Double labeled: blue - Isl1; orange - Hoxb1 (assay MGI:6430416).
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present Regionally restricted S2A' Co-expression with Hoxb1in splanchnic mesoderm and anterior foregut endoderm.
TS13: splanchnopleure Present Regionally restricted S2A' Co-expression with Hoxb1in splanchnic mesoderm and anterior foregut endoderm.

Specimen S2B: embryonic day 8.5 (more )
Note: Double labeled: blue - Isl1; orange - Hoxa1 (assay MGI:6430418).
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present Regionally restricted S2B Co-expression with Hoxb1in splanchnic mesoderm and anterior foregut endoderm.
TS13: splanchnopleure Present Regionally restricted S2B Co-expression with Hoxb1in splanchnic mesoderm and anterior foregut endoderm.

Specimen S2B': embryonic day 8.5 (more )
Note: Double labeled: blue - Isl1; orange - Hoxa1 (assay MGI:6430418).
Structure Level Pattern Image Note
TS13: splanchnopleure Present Regionally restricted S2B' Co-expression with Hoxa1 in splanchnic mesoderm.

Specimen S2C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: secondary heart field Present S2C

Specimen S2C': embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present S2C' Expresson in endoderm and second heart field.
TS13: secondary heart field Present S2C' Expresson in endoderm and second heart field.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory