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Gene Expression Data
Assay Details
Assay
Reference: J:272566 Yang R, et al., CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6423310
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase 3 (AF835)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S3F/H: embryonic day 16.5 (more )
Note: Double labeled: green - Casp3; red - Dlk1 (assay MGI:6423291).
Structure Level Pattern Image Note
TS24: liver Trace S3F , S3H Few apoptotic cells were detected in wild type at E16.5.
Specimen S3F'/H': embryonic day 16.5; Cdk5rap3tm1b(EUCOMM)Hmgu/Cdk5rap3tm1b(EUCOMM)Hmgu (more )
Note: Double labeled: green - Casp3; red - Dlk1 (assay MGI:6423291).
Structure Level Pattern Image Note
TS24: liver Present S3H' , S3F' Many apoptotic cells were observed in knockout livers at E16.5. Scarce Dlk1-labeled hepatocytes displayed activated-Casp3 staining.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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