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Gene Expression Data
Assay Details
Assay
Reference: J:150758 Richardson GD, et al., Dynamic expression of Syndecan-1 during hair follicle morphogenesis. Gene Expr Patterns. 2009 Sep;9(6):454-60
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6386656
Gene symbol: Sdc1
Gene name: syndecan 1
Antibody: 281-2
Detection system: Secondary antibody coupled to rhodamine
Assay notes: Fixative was methanol/acetone.
Results
Specimen 2A: embryonic day 13.5 (more )
Note: Undifferentiated dorsal skin.
Structure Level Pattern Image Note
TS21: epidermis Present Uniform 2A
TS21: dermis Absent 2A
Specimen 2B: embryonic day 14.5 (more )
Note: Early placode stage of hair follicle morphogenesis.
Structure Level Pattern Image Note
TS22: hair follicle dermal papilla Present 2B
TS22: epidermis Present Regionally restricted 2B Expression is in the outer suprabasal and differentiating layers of the epidermis.
TS22: hair epidermal placode Weak Regionally restricted 2B Expression is in the outer suprabasal and differentiating layers of the placode, is weak in the basal layer, and is absent from the newly formed placodes.
Specimen 2C: embryonic day 15.5 (more )
Note: Peg stage of hair follicle morphogenesis.
Structure Level Pattern Image Note
TS23: hair follicle dermal papilla Present 2C
TS23: epidermis Present Regionally restricted 2C Expression is in the suprabasal layers of the epidermis.
TS23: hair epidermal placode Absent 2C
Specimen 2D: embryonic day 16.5 (more )
Note: Peg stage of hair follicle morphogenesis.
Structure Level Pattern Image Note
TS24: hair follicle dermal papilla Present 2D
TS24: epidermis Present Regionally restricted 2D Expression is in the suprabasal layers of the epidermis.
TS24: hair epidermal placode Absent 2D
Specimen 2E: embryonic day 16.5 (more )
Note: Secondary hair follicle.
Structure Level Pattern Image Note
TS24: hair follicle dermal papilla Present 2E
TS24: hair epidermal placode Absent 2E
Specimen 2F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: hair follicle dermal papilla Present 2F
TS26: hair root sheath Weak 2F Expression is in the differentiating central column of the hair follicle epithelial cells.
Specimen 2G: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: hair bulb Present 2G Expression is throughout all the cells of the epithelial compartment in both the primary and secondary hair follicles, with highest levels in the differentiating central column of both follicle types.
TS27: hair follicle dermal papilla Weak 2G
Specimen 2H: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Strong 2H
TS28: hair follicle matrix region Strong Regionally restricted 2H Expression is in matrix keratinocytes.
TS28: hair follicle dermal papilla Weak 2H
Specimen 2H inset: postnatal day 6 (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Strong 2H inset
TS28: hair follicle matrix region Strong Regionally restricted 2H inset Expression is in matrix keratinocytes.
TS28: hair follicle dermal papilla Weak 2H inset
Specimen 3A: embryonic day 13.0 (more )
Note: Early placode stage 1 of hair development.
Structure Level Pattern Image Note
TS21: vibrissa dermal component Present 3A
TS21: vibrissa epidermal component Present Regionally restricted 3A During the progressive stages of hair morphogenesis expression becomes absent from the hair peg.
TS21: dermis Present Regionally restricted 3A Expression is in the condensed dermis surrounding the epithelial component of the hair follicle in the whisker pad.
Specimen 3B: embryonic day 13.0 (more )
Note: Stage 2 of hair development.
Structure Level Pattern Image Note
TS21: vibrissa dermal component Present 3B
TS21: vibrissa epidermal component Present Regionally restricted 3B During the progressive stages of hair morphogenesis expression becomes absent from the hair peg.
TS21: dermis Present Regionally restricted 3B Expression is in the condensed dermis surrounding the epithelial component of the hair follicle in the whisker pad.
Specimen 3C: embryonic day 13.0 (more )
Note: Stage 3-4 of hair development.
Structure Level Pattern Image Note
TS21: vibrissa dermal component Present 3C
TS21: vibrissa epidermal component Present Regionally restricted 3C During the progressive stages of hair morphogenesis expression becomes absent from the hair peg.
TS21: dermis Present Regionally restricted 3C Expression is in the condensed dermis surrounding the epithelial component of the hair follicle in the whisker pad.
Specimen 3D: embryonic day 13.0 (more )
Note: Stage 4-5 of hair development.
Structure Level Pattern Image Note
TS21: vibrissa dermal component Present 3D
TS21: vibrissa epidermal component Present Regionally restricted 3D During the progressive stages of hair morphogenesis expression becomes absent from the hair peg.
TS21: dermis Present Regionally restricted 3D Expression is in the condensed dermis surrounding the epithelial component of the hair follicle in the whisker pad.
Specimen 3E: embryonic day 13.0 (more )
Note: Stage 5-6 of hair development.
Structure Level Pattern Image Note
TS21: vibrissa dermal component Present 3E
TS21: vibrissa Weak Regionally restricted 3E Expression is in the hair peg inner root sheath.
TS21: vibrissa follicle Present Regionally restricted 3E Expression is in the epithelial cells of the follicle, with the highest levels associated with the central core of cells.
Specimen 3F: embryonic day 13.0 (more )
Note: Stage 7-8 of hair development.
Structure Level Pattern Image Note
TS21: vibrissa follicle Present Regionally restricted 3F Expression is highest in the inner and outer root sheath and the pre-cortex cells.
TS21: vibrissa dermal component Weak 3F
TS21: dermis Present Regionally restricted 3F Expression is at the follicle neck and in the condensed dermis surrounding the epithelial component of the hair follicle in the whisker pad.
Specimen 3G: embryonic day 13.0 (more )
Note: Stage 8-9 of hair development.
Structure Level Pattern Image Note
TS21: vibrissa follicle Present Regionally restricted 3G Expression is highest in the inner and outer root sheath and the pre-cortex cells.
TS21: dermis Present Regionally restricted 3G Expression is at the follicle neck and is absent in the dermal papilla.
TS21: vibrissa dermal component Absent 3G
Specimen 4A: embryonic day 18.0 (more )
Note: Tail skin stage 1 of hair development. Double labeled: red - Sdc1; green - Edar (assay MGI:6386658).
Structure Level Pattern Image Note
TS26: hair follicle dermal papilla Present 4A
TS26: hair epidermal placode Present Regionally restricted 4A Expression is in the basal cells of the placode.
Specimen 4B: embryonic day 18.0 (more )
Note: Tail skin stage 2 of hair development. Double labeled: red - Sdc1; green - Edar (assay MGI:6386658).
Structure Level Pattern Image Note
TS26: hair follicle dermal papilla Present 4B
TS26: hair epidermal placode Present Regionally restricted 4B Expression is in the basal cells of the placode.
Specimen 4C: embryonic day 18.0 (more )
Note: Tail skin stage 4 of hair development. Double labeled: red - Sdc1; green - Edar (assay MGI:6386658).
Structure Level Pattern Image Note
TS26: hair follicle dermal papilla Present 4C
TS26: hair epidermal placode Present Regionally restricted 4C Expression is in the basal cells of the placode.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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