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Gene Expression Data
Assay Details
Assay
Reference: J:270238 Wang L, et al., Dynamic expression of p75(NTR) and Lingo-1 during development of mouse retinofugal pathway. Neurosci Lett. 2018 Sep 7;686:106-111
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6386238
Gene symbol: Lingo1
Gene name: leucine rich repeat and Ig domain containing 1
Antibody: Anti-Lingo1 (07-678)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: retina Present Regionally restricted 1D Expression was detected in neuroepithelial cells that appear to migrate from the basal layer to vitreal regions of the retina. Immunoreactivity was not observed in the optic fiber layer.

Specimen 1E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 1E Expression was detected only in the ganglion cell layer with a weak signal in the optic fiber layer.

Specimen 1F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: retina Present Regionally restricted 1F The immunostaining pattern was maintained at E15.5, showing a preferential localization in the soma of retinal ganglion cells.

Specimen 2D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS22: optic disc Present Regionally restricted 2D Expression was detected on glial profiles that wrap around optic axon bundles at the optic disc. Immunoreactivity was not detected on the axons.

Specimen 2E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: optic disc Present Regionally restricted 2E Expression was detected on glial profiles that wrap around optic axon bundles at the optic disc. Immunoreactivity was not detected on the axons.

Specimen 2F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: optic disc Present Regionally restricted 2F Expression was detected on glial profiles that wrap around optic axon bundles at the optic disc. Immunoreactivity was not detected on the axons.

Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 4B , 4A Expression was detected in two cellular domains located caudally to the chiasm.

Specimen 4C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: optic stalk Present 4C Expression was most obvious on axons.
TS22: optic tract Present 4C Expression was most obvious on axons.
TS22: optic chiasma Present 4C

Specimen 4D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: optic chiasma Present 4D Expression was detected on axons.
TS23: optic stalk Present 4D Expression was detected on axons.
TS23: optic tract Present 4D Expression was detected on axons.

Specimen 4E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: optic chiasma Present 4E Expression was detected on axons.

Specimen 4G: embryonic day 13.5 (more )
Note: Double labeled: green - Lingo1; red - Fut4 (assay MGI:6386240).
Structure Level Pattern Image Note
TS21: optic chiasma Present 4G , 4I Expression was detected on chiasmatic neurons, which co-localized SSEA-1 (Fut4) staining.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory