About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:277316 Lukacs M, et al., Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival. Elife. 2019 Jun 24;8:e45248
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6383687
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: This antibody recognizes only the cleaved form of the protein.
Results
Specimen 6I: embryonic day 9.5 (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:6383683).
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Present Single cells 6I , 6J
TS15: migrating neural crest Present Single cells 6I , 6J
Specimen 6M: embryonic day 9.5; Pgap2clpex/Pgap2clpex (more )
Note: Double labeled: green - Casp3; red - Tfap2a (assay MGI:6383683).
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Strong Regionally restricted 6M , 6N Expression is in migrating cranial neural crest cells.
TS15: migrating neural crest Strong 6N , 6M
Specimen 6O: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present Single cells 6O
Specimen 6P: embryonic day 9.5; Pgap2clpex/Pgap2clpex (more )
Structure Level Pattern Image Note
TS15: midbrain-hindbrain junction Strong Regionally restricted 6P In this mutant there is increased expression bilaterally at the dorsolateral hinge points.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory