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Gene Expression Data
Assay Details
Assay
Reference: J:135151 Sigulinsky CL, et al., Vsx2/Chx10 ensures the correct timing and magnitude of Hedgehog signaling in the mouse retina. Dev Biol. 2008 May 15;317(2):560-75
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6383021
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: acTUBB3 antibody
Detection system: Alexa Fluor 488
Assay notes: The genetic background of the wild type specimens was either +/+ or heterozygous orJ. The authors report these mice to be phenotypically indistinguishable and considered to be equivalent.
Results
Specimen 3A/C: embryonic day 15.5 (more )
Note: Double labeled: green - Tubb3; blue - Gli1 (assay MGI:6383012).
Structure Level Pattern Image Note
TS23: retina Present Widespread 3A , 3C Expression in postmitotic neurons, extending to peripheral retina.
Specimen 3D/F: embryonic day 15.5; Vsx2or-J/Vsx2or-J (more )
Note: Double labeled: green - Tubb3; blue - Gli1 (assay MGI:6383012).
Structure Level Pattern Image Note
TS23: retina Present Regionally restricted 3D , 3F Expression domain is centrally restricted.
TS23: eye Present Regionally restricted 3F , 3D Authors report expression in cells that are not in retinal neuroepithelium. Expression in vitreal space.
Specimen 3G/I: embryonic day 12.5 (more )
Note: Double labeled: green - Tubb3; blue - Gli1 (assay MGI:6383012).
Structure Level Pattern Image Note
TS20: retina Present Regionally restricted 3I , 3G Expression is centrally restricted.
Specimen 3K/L: embryonic day 15.5; Vsx2or-J/Vsx2or-J (more )
Note: Double labeled: green - Tubb3; red - Pou4f2 (assay MGI:6383024).
Structure Level Pattern Image Note
TS23: retina Present Regionally restricted 3K , 3L Many of expressing cells co-express Pou4f2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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