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Gene Expression Data
Assay Details
Assay
Reference: J:134435 Anselme I, et al., Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes. Dev Biol. 2007 Apr 1;304(1):208-20
Assay type: RNA in situ
MGI Accession ID: MGI:6382582
Gene symbol: Six3
Gene name: sine oculis-related homeobox 3
Probe: Six3 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2D: embryonic day 8.0 (more )
Note: 6 somites. Also stained for En1 (assay MGI:6382583) and Hnf1b (Vhnf1; assay MGI:6382584); all purple.
Structure Level Pattern Image Note
TS12: future prosencephalon Present 2D Expression activated during gastrulation in anterior neural plate and persists during early somite stages.
Specimen 2P: embryonic day 9.5 (more )
Note: 22 somites. Double labeled: red - Six3; purple - En2 (assay MGI:6382583).
Structure Level Pattern Image Note
TS15: future forebrain Present 2P Authors report a smooth forebrain-midbrain boundary of expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory