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Gene Expression Data
Assay Details
Assay
Reference: J:281142 Wade AK, et al., LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet beta-cell function. J Biol Chem. 2019 Aug 2;294(31):11728-11740
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6382188
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: clone 39.4D5
Detection system: Secondary antibody
Results
Specimen 1E: embryonic day 15.5 (more )
Note: Triple labeled: blue - Isl1; red - Rnf40 (assay MGI:6382184); green - Ins1 (assay MGI:6382189) and Ins2 (assay MGI:6382191).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present 1E Merge , 1E Isl1
Specimen 1F: postnatal day 1 (more )
Note: Triple labeled: blue - Isl1; red - Rnf40 (assay MGI:6382184); green - Ins1 (assay MGI:6382189) and Ins2 (assay MGI:6382191).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present 1F Merge , 1F Isl1
Specimen 1G: postnatal month 3 (more )
Note: Triple labeled: blue - Isl1; red - Rnf40 (assay MGI:6382184); green - Ins1 (assay MGI:6382189) and Ins2 (assay MGI:6382191).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 1G Isl1 , 1G Merg
Specimen S1A: embryonic day 15.5 (more )
Note: Triple labeled: yellow - Isl1; red - Rnf40 (assay MGI:6382184); green - Neurog3 (assay MGI:6382192).
Structure Level Pattern Image Note
TS23: islets of Langerhans Present S1A Merge , S1A Isl1
Specimen S1B - left: postnatal day 1 (more )
Note: Triple labeled: blue - Isl1; red - Rnf40 (assay MGI:6382184); green - Ins1 (assay MGI:6382189) and Ins2 (assay MGI:6382191).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present S1B Ins/Isl1/Rnf40
Specimen S1B - right: postnatal day 1 (more )
Note: Triple labeled: white - Isl1; red - Ssbp3 (assay MGI:6382190); green - Ins1 (assay MGI:6382189) and Ins2 (assay MGI:6382191).
Structure Level Pattern Image Note
TS27: islets of Langerhans Present S1B Ins/Isl1/SSPB3
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory