Pdgfra RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:130196 Alfonsi F, et al., LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78
Assay type:	RNA in situ
MGI Accession ID:	MGI:6382027
Gene symbol:	Pdgfra
Gene name:	platelet derived growth factor receptor, alpha polypeptide

Probe:	PDGF-alphaR probe
Probe preparation:	Antisense labelled with fluorescein RNA

Results

2D ©

Specimen 2D: embryonic day 18.5 (more

)
Note: Double labeled: red - Pdgfra; green - Lifr (assay MGI:6382026).

Structure	Level	Pattern	Image	Note
TS26: facial nucleus	Present	Regionally restricted	2D	Expression in oligodendrocytes.

2E ©

Specimen 2E: embryonic day 18.5 (more

)
Note: Double labeled: red - Pdgfra; green - Lifr (assay MGI:6382026).

Structure	Level	Pattern	Image	Note
TS26: facial nucleus	Present	Regionally restricted	2E	Expression in oligodendrocytes.

Specimen E18.5 Lifrb-/- not shown: embryonic day 18.5; Lifr^tm1Imx/Lifr^tm1Imx (more

)

Structure	Level	Pattern	Image	Note
TS26: facial nucleus	Weak	Regionally restricted		Authors report 40% reduction in oligodendrocytes compared to control. Quanitification of expressing cells is presented in Table 1.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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