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Gene Expression Data
Assay Details
Assay
Reference: J:130185 Ellsworth BS, et al., Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6380634
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-CASP3
Detection system: fluorescein
Results
Specimen 1E: embryonic day 11.5 (more )
Note: Double labeled: green - Casp3; red - Pitx1 (assay MGI:6380633).
Structure Level Pattern Image Note
TS19: Rathke's pouch Ambiguous 1E
Specimen 1F: embryonic day 11.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Note: Double labeled: green - Casp3; red - Pitx1 (assay MGI:6380633).
Structure Level Pattern Image Note
TS19: Rathke's pouch Present Regionally restricted 1F Significant increase in apoptotic cells in ventral portion of Rathke's pouch. Expression along epithelial connection between oral cavity and pouch.
Specimen 1G: embryonic day 12.5 (more )
Note: Double labeled: green - Casp3; red - Pitx1 (assay MGI:6380633).
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Ambiguous 1G
Specimen 1H: embryonic day 12.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Note: Double labeled: green - Casp3; red - Pitx1 (assay MGI:6380633).
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present Regionally restricted 1H Significant increase in apoptotic cells in ventral portion of Rathke's pouch.
Specimen E14.5 Wild type not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pituitary gland Ambiguous
Specimen E14.5 Mutant not shown: embryonic day 14.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS22: pituitary gland Present Regionally restricted Significant increase in apoptotic cells in ventral portion of Rathke's pouch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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