Gene Expression Data
Assay Details
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Assay
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Reference:
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J:169193
Walsh T, et al., Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet. 2010 Jul 9;87(1):101-9
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6376155
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Gene symbol:
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Tjp2
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Gene name:
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tight junction protein 2
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Antibody:
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anti-ZO-2 (#2847)
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Detection system:
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Secondary antibody coupled to Alexa Fluor 594
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Results
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Specimen
3C upper:
embryonic day 16.5
(more  )
Note: Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
Specimen
3C upper:
(close  )
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Genetic Background:
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C3H
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: cochlea epithelium |
Present |
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3C upper right
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3C upper left
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Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
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Specimen
3C middle:
postnatal day 0
(more )
Note: Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
Specimen
3C middle:
(close )
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Genetic Background:
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C3H
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea epithelium |
Present |
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3C middle left
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3C middle right
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Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
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Specimen
3D:
embryonic day 16.5
(more )
Note: Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
Specimen
3D:
(close )
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Genetic Background:
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C3H
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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Note:
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Double labeled: red - Tjp2; green - Myo6 (assay MGI:6376157).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: saccule epithelium |
Present |
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3D left
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3D right
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Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
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Specimen
not shown:
embryonic day 16.5
(more )
Specimen
not shown:
(close )
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Genetic Background:
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C3H
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: utricle epithelium |
Present |
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Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
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| TS24: semicircular canal epithelium |
Present |
Regionally restricted |
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Expressed in the crista. Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
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Specimen
not shown:
postnatal day 0
(more )
Specimen
not shown:
(close )
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Genetic Background:
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C3H
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: crista ampullaris |
Present |
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Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
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| TS27: utricle epithelium |
Present |
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Expressed mainly at cell junctions and also in the cytoplasm and nuclei of hair cells and adjacent supporting cells.
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Analysis Tools