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Gene Expression Data
Assay Details
Assay
Reference: J:228706 Chandramouli A, et al., Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution. Breast Cancer Res. 2013;15(6):R111
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6369736
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 11A: postnatal adult; Ltbp1tm1Vlcg/Ltbp1+ (more )
Note: 6-week-old pubertal mouse. Double labeled: green - Acta2; red - Ltbp1 (assay MGI:6369717).
Structure Level Pattern Image Note
TS28: mammary gland myoepithelium Present 11A merge , 11A SMA Expression is in basal myoepithelial cells of mature ducts and is absent in cap cells of the terminal end bud.
TS28: mammary duct terminal end bud Absent 11A SMA , 11A merge Expression is absent in cap cells of the terminal end bud.
Specimen 11B: postnatal adult; Ltbp1tm1Vlcg/Ltbp1+ (more )
Note: 6-week-old pubertal mouse. Double labeled: green - Acta2; red - Ltbp1 (assay MGI:6369717).
Structure Level Pattern Image Note
TS28: mammary gland myoepithelium Present Regionally restricted 11B merge , 11B SMA Expression is in basal myoepithelial cells of mature ducts.
Specimen 11C: postnatal adult; Ltbp1tm1Vlcg/Ltbp1+ (more )
Note: 6-week-old pubertal mouse. Double labeled: green - Acta2; red - Eln (assay MGI:6369733).
Structure Level Pattern Image Note
TS28: mammary gland myoepithelium Present Regionally restricted 11C SMA , 11C merge Expression is in basal myoepithelial cells of mature ducts.
Specimen 11D: postnatal adult; Ltbp1tm1Vlcg/Ltbp1+ (more )
Note: Pregnancy day 14.5. Double labeled: green - Acta2; red - Ltbp1 (assay MGI:6369717).
Structure Level Pattern Image Note
TS28: mammary gland myoepithelium Present Regionally restricted 11D SMA , 11D merge Expression is in basal myoepithelial cells of mature ducts.
TS28: mammary gland alveolus Strong Regionally restricted 11D SMA , 11D merge Expression is in basal cells.
Specimen 11E: postnatal adult; Ltbp1tm1Vlcg/Ltbp1+ (more )
Note: Pregnancy day 14.5. Double labeled: green - Acta2; red - Eln (assay MGI:6369733).
Structure Level Pattern Image Note
TS28: mammary gland myoepithelium Present Regionally restricted 11E SMA , 11E merge Expression is in basal myoepithelial cells of mature ducts.
TS28: mammary gland alveolus Strong Regionally restricted 11E merge , 11E SMA Expression is in basal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory