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Gene Expression Data
Assay Details
Assay
Reference: J:103443 Wilhelm D, et al., Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev Biol. 2005 Nov 1;287(1):111-24
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6356021
Gene symbol: Sry
Gene name: sex determining region of Chr Y
Antibody: Anti-Sry
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C XY embryo: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS19: urogenital ridge Present Scattered 1C XY embryo Expression in cells scattered throughout XY genital ridge.
Specimen 1C XX embryo: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS19: urogenital ridge Absent 1C XX embryo No expression in XX genital ridge.
Specimen 1D: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS19: urogenital ridge Present Regionally restricted 1D Expression only in somatic cells of genital ridge.
Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: urogenital ridge Present Punctate 1E Authors report punctate nuclear localization of expression.
Specimen 2 11ts: embryonic day 10.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS18: urogenital ridge Present Regionally restricted 2_11ts Authors report onset of protein expression at 11 ts. Expression in a small number of cells in center of genital ridge.
Specimen 2 13ts: embryonic day 11.0 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS18: urogenital ridge Present Regionally restricted 2_13ts Increase in number of expressing cells. Expression domain expanded from center of genital ridge to pole.
Specimen 2 15ts: embryonic day 11.0 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS18: urogenital ridge Present Regionally restricted 2_15ts Increase in number of expressing cells. Expression domain expanded from center of genital ridge to pole.
Specimen 2 18ts: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS19: urogenital ridge Present Regionally restricted 2_18ts Expression in somatic cells along entire length of gonad.
Specimen 2 20ts: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS19: urogenital ridge Present Regionally restricted 2_20ts Domain of expression receded in rostral-to-caudal wave.
Specimen 2 23 ts: embryonic day 12.0 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS20: urogenital ridge Present Regionally restricted 2_23ts Domain of expression receded in rostral-to-caudal wave.
Specimen 2 25ts: embryonic day 12.0 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS20: urogenital ridge Present Regionally restricted 2_25ts Domain of expression receded in rostral-to-caudal wave.
Specimen 2 30ts: embryonic day 12.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS20: urogenital ridge Present Regionally restricted 2_30ts Expression in cells at caudal pole.
Specimen 2 34ts: embryonic day 13.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS21: urogenital ridge Absent 2_34ts Expression completely disappeared by 34 ts.
Specimen 3A 14ts: embryonic day 11.0 (more )
Note: Double labeled: green - Sry; red - Sox9 (assay MGI:6356025).
Structure Level Pattern Image Note
TS18: urogenital ridge Present Regionally restricted 3A 14ts Some but not all expressing cells also express Sox9.
Specimen 3A 16ts: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Sox9 (assay MGI:6356025).
Structure Level Pattern Image Note
TS19: urogenital ridge Present Regionally restricted 3A 16ts Expression in most Sox9-expressing cells.
Specimen 3A 18ts: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Sox9 (assay MGI:6356025).
Structure Level Pattern Image Note
TS19: urogenital ridge Present Regionally restricted 3A 18ts Expression down-regulated in some cells.
Specimen 3A 25ts: embryonic day 12.0 (more )
Note: Double labeled: green - Sry; red - Sox9 (assay MGI:6356025).
Structure Level Pattern Image Note
TS20: urogenital ridge Present Regionally restricted 3A 25ts Expression down-regulated in some cells.
Specimen 3B 18ts: embryonic day 11.5 (more )
Note: Double labeled: green - Sry; red - Sox9 (assay MGI:6356025).
Structure Level Pattern Image Note
TS19: urogenital ridge Present Regionally restricted 3B Authors report a variety of different expression levels in somatic cells of XY gonads.
Specimen 3C left: embryonic day 12.5 (more )
Note: Double labeled: green - Sry; red - Pecam1 (assay MGI:6356022).
Structure Level Pattern Image Note
TS20: urogenital ridge Present 3C left
Specimen 3D 14ts: embryonic day 11.0 (more )
Note: Double labeled: green - Sry; red - Sox9 (assay MGI:6356025).
Structure Level Pattern Image Note
TS18: urogenital ridge Present 3D
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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